Pavel Pitule
Overview
Explore the profile of Pavel Pitule including associated specialties, affiliations and a list of published articles.
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23
Citations
364
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Recent Articles
1.
Maceckova D, Vankova L, Bufka J, Hosek P, Moravec J, Pitule P
Mol Biol Rep
. 2024 Dec;
52(1):57.
PMID: 39692897
Background: The genetic and epigenetic alterations observed in acute myeloid leukemia (AML) contribute to its heterogeneity, influencing disease progression response to therapy, and patient outcomes. The use of antisense oligonucleotides...
2.
Maceckova D, Vankova L, Holubova M, Jindra P, Klieber R, Jandova E, et al.
Mol Biol Rep
. 2024 Apr;
51(1):521.
PMID: 38625438
Acute myeloid leukaemia (AML) is a complex haematological malignancy characterised by diverse genetic alterations leading to abnormal proliferation of myeloid precursor cells. One of the most significant genetic alterations in...
3.
Kolencik D, Narayan S, Thiele J, McKinley D, Gerdtsson A, Welter L, et al.
Cancers (Basel)
. 2022 Feb;
14(3).
PMID: 35158910
The liquid biopsy has the potential to improve current clinical practice in oncology by providing real-time personalized information about a patient's disease status and response to treatment. In this study,...
4.
Navvabi N, Kolikova P, Hosek P, Zitricky F, Navvabi A, Vycital O, et al.
Cancer Genomics Proteomics
. 2021 Apr;
18(3):295-306.
PMID: 33893082
Background/aim: Colorectal cancer is currently the third leading cause of cancer-related deaths and recently, alternative splicing has risen as its important regulator and potential treatment target. In the present study,...
5.
Machuldova A, Holubova M, Caputo V, cedikova M, Jindra P, Houdova L, et al.
Front Immunol
. 2021 Apr;
12:651751.
PMID: 33868289
Natural killer cells possess key regulatory function in various malignant diseases, including acute myeloid leukemia. NK cell activity is driven by signals received through ligands binding activating or inhibitory receptors....
6.
Dekojova T, Houdova L, Fatka J, Pitule P, Ostasov P, Caputo V, et al.
J Clin Med
. 2020 Nov;
9(11).
PMID: 33138211
Killer-immunoglobulin-like receptors (KIRs) are critical natural killer (NK) cell regulators. The expression of KIRs is a dynamic process influenced by many factors. Their ligands-HLA(Human Leukocyte Antigen) class I molecules-are expressed...
7.
Fiala O, Sorejs O, Hosek P, Liska V, Vycital O, Bruha J, et al.
Cancer Genomics Proteomics
. 2020 Aug;
17(5):605-613.
PMID: 32859639
Background/aim: MicroRNAs (miRs) play an important role in the regulation of cancer-related processes and are promising candidates for cancer biomarkers. The aim of the study was to evaluate the association...
8.
Kolencik D, Shishido S, Pitule P, Mason J, Hicks J, Kuhn P
Cancers (Basel)
. 2020 May;
12(6).
PMID: 32471160
Colorectal carcinoma (CRC) is characterized by wide intratumor heterogeneity with general genomic instability and there is a need for improved diagnostic, prognostic, and therapeutic tools. The liquid biopsy provides a...
9.
Ostasov P, Tuma J, Pitule P, Moravec J, Houdek Z, Vozeh F, et al.
Int J Mol Sci
. 2020 May;
21(10).
PMID: 32456161
Neural stem cells are fundamental to development of the central nervous system (CNS)-as well as its plasticity and regeneration-and represent a potential tool for neuro transplantation therapy and research. This...
10.
Tichanek F, Salomova M, Jedlicka J, Kuncova J, Pitule P, Macanova T, et al.
Sci Rep
. 2020 Mar;
10(1):5418.
PMID: 32214165
Spinocerebellar ataxia 1 (SCA1) is a devastating neurodegenerative disease associated with cerebellar degeneration and motor deficits. However, many patients also exhibit neuropsychiatric impairments such as depression and apathy; nevertheless, the...