Pavel Kunes
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Explore the profile of Pavel Kunes including associated specialties, affiliations and a list of published articles.
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25
Citations
104
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Recent Articles
1.
Kudlova M, Kolackova M, Kunes P, Lonsky V, Mandak J, Andrys C, et al.
Acta Medica (Hradec Kralove)
. 2017 Aug;
50(3):187-193.
PMID: 28795943
Background: Myeloid cells are extensively activated in patients undergoing cardiosurgical operations. It is supposed that this activation is more profound in patients operated with cardiopulmonary bypass (CPB) ("on-pump") in comparison...
2.
Holubcova Z, Kunes P, Mandak J, Vlaskova D, Kolackova M, Holmannova D, et al.
Perfusion
. 2016 Nov;
32(4):269-278.
PMID: 27852958
Objectives: The aim was to evaluate the association between perioperative inflammatory biomarkers and atrial fibrillation (AF) in cardiac surgical patients. Methods: Forty-two patients undergoing cardiac surgery were divided into three...
3.
Holmannova D, Kolackova M, Mandak J, Kunes P, Holubcova Z, Holubec T, et al.
Perfusion
. 2016 Sep;
32(2):141-150.
PMID: 27625334
Objective: Cardiac surgery is known to trigger a systemic inflammatory response. While the use of conventional cardiopulmonary bypass (CPB) results in profound inflammation, modified mini-CPB is considered less harmful. We...
4.
Holmannova D, Kolackova M, Kunes P, Krejsek J, Mandak J, Andrys C
Perfusion
. 2015 Oct;
31(5):391-400.
PMID: 26503949
Objective: We measured and compared changes in the percentage of cells expressing CD80, CD86, CD40, HLA-DR and the expression of these molecules on B cells and monocytes of patients who...
5.
Could pentraxin 3 be a new diagnostic marker for excessive inflammatory response in cardiac surgery?
Holubcova Z, Kunes P, Mandak J, Kolackova M, Andrys C, Krejsek J, et al.
Thorac Cardiovasc Surg
. 2014 Aug;
62(8):670-6.
PMID: 25148605
Background: The aim of this study was to compare the dynamics of two inflammatory response biomarkers pentraxin 3 (PTX3) and C-reactive protein (CRP) after cardiac surgery with particular regard to...
6.
Krejsek J, Kolackova M, Mandak J, Kunes P, Holubcova Z, Holmannova D, et al.
Acta Medica (Hradec Kralove)
. 2013 Sep;
56(2):57-66.
PMID: 24069659
Cardiac surgery is inseparably linked to the activation of innate immunity cells recognizing danger signals of both endogenous and exogenous origin via pattern recognition receptors such as TLR receptors. Therefore,...
7.
Holmannova D, Kolackova M, Kondelkova K, Kunes P, Krejsek J, Ctirad A
Acta Medica (Hradec Kralove)
. 2012 Oct;
55(2):59-65.
PMID: 23101267
CD200 and its receptor were recognized as having the multiple immunoregulatory functions. Their immunoregulatory, suppressive, and tolerogenic potentials could be very effectively exploited in the treatment of many diseases, e.g....
8.
Holmannova D, Kolackova M, Kondelkova K, Kunes P, Krejsek J, Andrys C
Acta Medica (Hradec Kralove)
. 2012 Jun;
55(1):12-7.
PMID: 22696929
CD200/CD200R are highly conserved type I paired membrane glycoproteins that belong to the Ig superfamily containing a two immunoglobulin-like domain (V, C). CD200 is broadly distributed in a variety of...
9.
Kolackova M, Krejsek J, Svitek V, Kunes P, Mandak J, Holubcova Z, et al.
Mediators Inflamm
. 2012 Apr;
2012:152895.
PMID: 22529517
Interleukin-10 (IL-10) is considered to be a cytokine with potent anti-inflammatory properties, which have been previously linked to increased incidence of sepsis. The level of IL-10 is elevated by cardiac...
10.
Kunes P, Holubcova Z, Kolackova M, Krejsek J
Acta Medica (Hradec Kralove)
. 2010 Dec;
53(3):125-9.
PMID: 21171524
The recently recognized cytokine interleukin-33 and its receptor ST2 play a favorable role during atherogenesis by inducing a Th1 --> Th2 shift of the immune response. IL-33 also protects the...