Pavel Krsek
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Explore the profile of Pavel Krsek including associated specialties, affiliations and a list of published articles.
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111
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1574
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Recent Articles
1.
Splitkova B, Mackova K, Koblizek M, Holubova Z, Kyncl M, Bukacova K, et al.
Epilepsia
. 2024 Dec;
66(3):632-647.
PMID: 39724384
Objective: We comprehensively characterized a large pediatric cohort with focal cortical dysplasia (FCD) type 1 to expand the phenotypic spectrum and to identify predictors of postsurgical outcomes. Methods: We included...
2.
Stevering C, Lequin M, Szczepaniak K, Sadowski K, Ishrat S, De Luca A, et al.
Epilepsia
. 2024 Dec;
66(2):356-368.
PMID: 39641935
Objective: Previous retrospective studies have reported vigabatrin-associated brain abnormalities on magnetic resonance imaging (VABAM), although clinical impact is unknown. We evaluated the association between vigabatrin and predefined brain magnetic resonance...
3.
Kudr M, Janca R, Jahodova A, Belohlavkova A, Ebel M, Bukacova K, et al.
Epilepsia
. 2024 Dec;
66(2):444-457.
PMID: 39636170
Objective: Epilepsy surgery in the operculoinsular cortex is challenging due to the difficult delineation of the epileptogenic zone and the high risk of postoperative deficits. Methods: Pre- and postsurgical data...
4.
Hammer J, Kajsova M, Kalina A, Krysl D, Fabera P, Kudr M, et al.
Commun Biol
. 2024 Sep;
7(1):1105.
PMID: 39251869
Antagonistic activity of brain networks likely plays a fundamental role in how the brain optimizes its performance by efficient allocation of computational resources. A prominent example involves externally/internally oriented attention...
5.
Stovickova L, Hansikova H, Hanzalova J, Musova Z, Semjonov V, Stovicek P, et al.
J Neurol
. 2024 Mar;
271(6):3439-3454.
PMID: 38520521
This study presents an in-depth analysis of mitochondrial enzyme activities in Friedreich's ataxia (FA) patients, focusing on the Electron Transport Chain complexes I, II, and IV, the Krebs Cycle enzyme...
6.
Sanders M, Van der Wolf I, Jansen F, Aronica E, Helmstaedter C, Racz A, et al.
Neurology
. 2024 Jan;
102(4):e208007.
PMID: 38290094
Background And Objective: Patients with presumed nonlesional focal epilepsy-based on either MRI or histopathologic findings-have a lower success rate of epilepsy surgery compared with lesional patients. In this study, we...
7.
Sedlackova L, Sterbova K, Vlckova M, Seeman P, Zarubova J, Marusic P, et al.
Eur J Paediatr Neurol
. 2023 Nov;
48:17-29.
PMID: 38008000
Objective: Developmental and epileptic encephalopathies (DEEs) are a group of severe, early-onset epilepsies characterised by refractory seizures, developmental delay, or regression and generally poor prognosis. DEE are now known to...
8.
Huschner F, Glowacka-Walas J, Mills J, Klonowska K, Lasseter K, Asara J, et al.
Nat Commun
. 2023 Nov;
14(1):7664.
PMID: 37996417
We present a comprehensive multi-omic analysis of the EPISTOP prospective clinical trial of early intervention with vigabatrin for pre-symptomatic epilepsy treatment in Tuberous Sclerosis Complex (TSC), in which 93 infants...
9.
Straka B, Koblizek M, Splitkova B, Valkovicova R, Krskova L, Kalinova M, et al.
Epilepsia Open
. 2023 Nov;
9(1):424-431.
PMID: 37943122
Focal cortical dysplasia (FCD) represents the most common cause of drug-resistant epilepsy in adult and pediatric surgical series. However, genetic factors contributing to severe phenotypes of FCD remain unknown. We...
10.
Straka B, Splitkova B, Vlckova M, Tesner P, Rezacova H, Krskova L, et al.
Eur J Paediatr Neurol
. 2023 Oct;
47:80-87.
PMID: 37812946
Objective: Although genetic causes of drug-resistant focal epilepsy and selected focal malformations of cortical development (MCD) have been described, a limited number of studies comprehensively analysed genetic diagnoses in patients...