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Pavan Prabhala

Explore the profile of Pavan Prabhala including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 128
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Recent Articles
1.
Malmros K, Kirova N, Kotarsky H, Carlsen D, Mansour M, Magnusson M, et al.
J Cancer Res Clin Oncol . 2024 Oct; 150(10):472. PMID: 39441367
Purpose: The aim of this study was to set up reliable and reproducible culture conditions for 3D tumoroids derived from non-small cell lung cancer (NSCLC) cell lines to enable greater...
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Siddhuraj P, Jonsson J, Alyamani M, Prabhala P, Magnusson M, Lindstedt S, et al.
Front Immunol . 2022 Aug; 13:924244. PMID: 35983043
Background: The mast cell-specific metalloprotease CPA3 has been given important roles in lung tissue homeostasis and disease pathogenesis. However, the dynamics and spatial distribution of mast cell CPA3 expression in...
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Wijk S, Prabhala P, Lofdahl A, Nybom A, Lang S, Brunnstrom H, et al.
Cells . 2022 Mar; 11(6). PMID: 35326483
Cell-based therapies hold great promise in re-establishing organ function for many diseases, including untreatable lung diseases such as idiopathic pulmonary fibrosis (IPF). However, many hurdles still remain, in part due...
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Wijk S, Prabhala P, Michalikova B, Sommarin M, Doyle A, Lang S, et al.
Am J Respir Cell Mol Biol . 2021 Mar; 65(1):103-113. PMID: 33789072
Airway basal cells are crucial for regeneration of the human lung airway epithelium and are believed to be important contributors to chronic obstructive pulmonary disease (COPD) and other lung disorders....
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Hultmark S, Baudet A, Schmiderer L, Prabhala P, Palma-Tortosa S, Sanden C, et al.
Haematologica . 2020 Aug; 106(10):2566-2577. PMID: 32855276
Combination treatment has proven effective for patients with acute promyelocytic leukemia, exemplifying the importance of therapy targeting multiple components of oncogenic regulation for a successful outcome. However, recent studies have...
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Prabhala P, Wright D, Robbe P, Bitter C, Pera T, Ten Hacken N, et al.
Am J Physiol Lung Cell Mol Physiol . 2019 Sep; 317(6):L768-L777. PMID: 31553662
Airway inflammation and remodeling are characteristic features of asthma, with both contributing to airway hyperresponsiveness (AHR) and lung function limitation. Airway smooth muscle (ASM) accumulation and extracellular matrix deposition are...
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Moosavi S, Prabhala P, Ammit A
Respir Res . 2017 Aug; 18(1):154. PMID: 28797290
Mitogen-activated protein kinase (MAPK) phosphatase 1 (MKP-1) is a protein with anti-inflammatory properties and the archetypal member of the dual-specificity phosphatases (DUSPs) family that have emerged over the past decade...
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Rahman M, Prabhala P, Rumzhum N, Patel B, Wickop T, Hansbro P, et al.
Int J Biochem Cell Biol . 2016 Aug; 78:279-287. PMID: 27477309
Corticosteroids are effective anti-inflammatory therapies widely utilized in chronic respiratory diseases. But these medicines can lose their efficacy during respiratory infection resulting in disease exacerbation. Further in vitro research is...
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Prabhala P, Bunge K, Ge Q, Ammit A
J Cell Physiol . 2016 Jan; 231(10):2153-8. PMID: 26825339
Exaggerated cytokine secretion drives pathogenesis of a number of chronic inflammatory diseases, including asthma. Anti-inflammatory pharmacotherapies, including corticosteroids, are front-line therapies and although they have proven clinical utility, the molecular...