Paulo Rodrigues-Santos
Overview
Explore the profile of Paulo Rodrigues-Santos including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
551
Followers
0
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Recent Articles
1.
Rodrigues-Santos P, Almeida J, Sousa L, Couceiro P, Martinho A, Rodrigues J, et al.
Front Immunol
. 2025 Feb;
16:1516793.
PMID: 40007535
Soft tissue sarcomas (STS) encompass over 50 histologic subtypes, representing more than 1% of solid tumors. Standard treatments include surgical resection and therapies such as anthracyclines or trabectedin for advanced...
2.
Almeida J, Sousa L, Couceiro P, Andrade T, Alves V, Martinho A, et al.
Front Immunol
. 2024 Nov;
15:1391840.
PMID: 39502689
Studying the tumor microenvironment and surrounding lymph nodes is the main focus of current immunological research on soft tissue sarcomas (STS). However, due to the restricted opportunity to examine tumor...
3.
Oliveira I, Rodrigues-Santos P, Ferreira L, Pires das Neves R
Biomater Sci
. 2024 Oct;
12(23):5933-5960.
PMID: 39441658
Cancer is becoming the main public health problem globally. Conventional chemotherapy approaches are slowly being replaced or complemented by new therapies that avoid the loss of healthy tissue, limit off-targets,...
4.
Domingues N, Catarino S, Cristovao B, Rodrigues L, Carvalho F, Sarmento M, et al.
EMBO J
. 2024 Jul;
43(17):3627-3649.
PMID: 39044100
A robust and efficient cellular response to lysosomal membrane damage prevents leakage from the lysosome lumen into the cytoplasm. This response is understood to happen through either lysosomal membrane repair...
5.
Goncalves M, Rodrigues-Santos P, Januario C, Cosentino M, Pereira F
Int Immunopharmacol
. 2024 Apr;
133:112062.
PMID: 38652967
Parkinson's Disease (PD) is the second most common neurodegenerative disease where central and peripheral immune dysfunctions have been pointed out as a critical component of susceptibility and progression of this...
6.
Goncalves M, Furgiuele A, Rasini E, Legnaro M, Ferrari M, Luini A, et al.
Eur J Pharmacol
. 2024 Feb;
968:176420.
PMID: 38367683
Background: Proinflammatory cytokines powerfully induce the rate-limiting enzyme indoleamine 2, 3-dioxygenase-1 (IDO-1) in dendritic cells (DCs) and monocytes, it converts tryptophan (Trp) into L-kynurenine (KYN), along the kynurenine pathway (KP)....
7.
Arnaut Z, Pinto S, Aroso R, Amorim A, Lobo C, Schaberle F, et al.
Photochem Photobiol Sci
. 2023 Sep;
22(11):2607-2620.
PMID: 37755667
The COVID-19 pandemic exposes our vulnerability to viruses that acquire the ability to infect our cells. Classical disinfection methods are limited by toxicity. Existing medicines performed poorly against SARS-CoV-2 because...
8.
Almeida J, Casanova J, Santos-Rosa M, Tarazona R, Solana R, Rodrigues-Santos P
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36769064
CD56+ T cells are generally recognized as a distinct population of T cells and are categorized as NKT-like cells. Although our understanding of NKT-like cells is far from satisfactory, it...
9.
Masin P, Visentin H, Elpidio L, Maria Sell A, Visentainer L, de Lima Neto Q, et al.
Front Genet
. 2022 Oct;
13:952219.
PMID: 36313452
Leprosy is a chronic disease and also a global health issue, with a high number of new cases per year. Toll-like receptors can respond to mycobacterial molecules in the early...
10.
Amorim M, Martins B, Caramelo F, Goncalves C, Trindade G, Simao J, et al.
Front Med (Lausanne)
. 2022 Jun;
9:873483.
PMID: 35692536
Purpose: Tear fluid biomarkers may offer a non-invasive strategy for detecting diabetic patients with increased risk of developing diabetic retinopathy (DR) or increased disease progression, thus helping both improving diagnostic...