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Pauline McFarlane

Explore the profile of Pauline McFarlane including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Bournazos S, Bournazou I, Murchison J, Wallace W, McFarlane P, Hirani N, et al.
Respiration . 2010 Nov; 81(2):142-9. PMID: 21109729
Background: Several genes exhibit copy number variation (CNV), including FCGR3B which encodes the IgG receptor FcγRIIIb. Engagement of Fcγ receptors by IgG complexes may contribute to the pathogenesis of idiopathic...
2.
Bournazos S, Grinfeld J, Alexander K, Murchison J, Wallace W, McFarlane P, et al.
BMC Pulm Med . 2010 Oct; 10:51. PMID: 20929558
Background: A significant genetic component has been described for idiopathic pulmonary fibrosis (IPF). The R131H (rs1801274) polymorphism of the IgG receptor FcγRIIa determines receptor affinity for IgG subclasses and is...
3.
Bournazos S, Bournazou I, Murchison J, Wallace W, McFarlane P, Hirani N, et al.
Lung . 2010 Oct; 188(6):475-81. PMID: 20924590
An excess of neutrophils in the alveoli and lung interstitium has been described in idiopathic pulmonary fibrosis (IPF). Engagement of neutrophil Fcγ receptors with IgG complexes may contribute to the...