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Paula Serrao

Explore the profile of Paula Serrao including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 225
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Recent Articles
1.
Oliveira A, Azevedo M, Seixas R, Silva S, Martinho R, Serrao P, et al.
Neuropharmacology . 2025 Feb; 271:110382. PMID: 39988278
Adrenaline (Ad) strengthens contextual fear memory by increasing blood glucose, possibly enhancing hippocampus acetylcholine synthesis. Nevertheless, it is unclear if peripheral Ad influences the cholinergic system, contributing to contextual fear...
2.
Benfeito S, Albuquerque B, Sequeira L, Lima C, Chavarria D, Serrao P, et al.
J Med Chem . 2024 Oct; 67(20):18384-18399. PMID: 39374514
A new library of non-nitrocatechol compounds (HetCAMs) was developed and their efficacy was compared to tolcapone, a standard COMT inhibitor for PD. Compound emerged as the most potent inhibitor, showing...
3.
Oliveira A, Azevedo M, Seixas R, Martinho R, Serrao P, Moreira-Rodrigues M
Mol Neurobiol . 2023 Nov; 61(5):2784-2797. PMID: 37938511
Adrenaline (Ad) and glucose released into the bloodstream during stress may strengthen contextual fear memory. However, no previous studies have detached the effects of glucose from Ad in this paradigm....
4.
Oliveira A, Seixas R, Pereira F, Azevedo M, Martinho R, Serrao P, et al.
Life Sci . 2023 Jun; 328:121881. PMID: 37356751
Aims: Adrenaline enhances contextual fear memory consolidation possibly by activating liver β-adrenoceptors causing transient hyperglycaemia. Contrastingly, insulin-induced hypoglycaemia may culminate in blood adrenaline increment, hidering the separation of each hormone's...
5.
Pereira-Silva R, Serrao P, Neto F, Martins I
Neurobiol Pain . 2023 Mar; 13:100123. PMID: 36915290
The loss of diffuse noxious inhibitory controls (DNIC) is recognized as a predictor of chronic pain. Mechanistically, DNIC produces analgesia by a heterotopically applied conditioning-noxious stimulus (CS) and yet underexplored...
6.
Martins E, Serrao P, Leonardi-Figueiredo M, Ravanelli L, Serenza F, Mattiello S, et al.
Physiother Theory Pract . 2022 Dec; 40(5):962-972. PMID: 36482746
Introduction: Propulsive wheelchair capacity may be influenced by arm muscle performance. To determine whether children and adolescent wheelchair-users with spina bifida show reduced arm muscle strength compared to their typically...
7.
Reina-Couto M, Santos-Oliveira M, Pereira-Terra P, Silva-Pereira C, Quelhas-Santos J, Duarte A, et al.
Biomedicines . 2022 Nov; 10(11). PMID: 36359365
Cysteinyl leukotrienes (CysLT) are potent vascular leakage-promoting agents but have been scarcely explored in human septic shock (SS). We evaluated CysLT at admission and during hospitalization and their correlation with...
8.
Chavarria D, Benfeito S, Soares P, Lima C, Garrido J, Serrao P, et al.
Eur J Med Chem . 2022 Sep; 243:114740. PMID: 36116233
Increased oxidative stress (OS) and depletion of nigrostriatal dopamine (DA) are closely linked to the neurodegeneration observed in Parkinson's Disease (PD). Caffeic acid (CA)-based antioxidants were developed, and their inhibitory...
9.
Reina-Couto M, Silva-Pereira C, Pereira-Terra P, Quelhas-Santos J, Bessa J, Serrao P, et al.
Front Physiol . 2022 Aug; 13:965611. PMID: 36035482
Inflammation-driven endothelitis seems to be a hallmark of acute heart failure (AHF) and cardiogenic shock (CS). Endocan, a soluble proteoglycan secreted by the activated endothelium, contributes to inflammation and endothelial...
10.
Farinha-Ferreira M, Rei N, Fonseca-Gomes J, Miranda-Lourenco C, Serrao P, Vaz S, et al.
Neuropharmacology . 2022 Jun; 214:109155. PMID: 35660545
Chronic adolescent cannabinoid receptor agonist exposure has been shown to lead to persistent increases in depressive-like behaviors. This has been a key obstacle to the development of cannabinoid-based therapeutics. However,...