Paula Rhana
Overview
Explore the profile of Paula Rhana including associated specialties, affiliations and a list of published articles.
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13
Citations
62
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Recent Articles
1.
Rhana P, Matsumoto C, Fong Z, Costa A, Del Villar S, Dixon R, et al.
Proc Natl Acad Sci U S A
. 2024 Jun;
121(25):e2318535121.
PMID: 38865270
The heart beats approximately 100,000 times per day in humans, imposing substantial energetic demands on cardiac muscle. Adenosine triphosphate (ATP) is an essential energy source for normal function of cardiac...
2.
Matsumoto C, ODwyer S, Manning D, Hernandez-Hernandez G, Rhana P, Fong Z, et al.
Commun Biol
. 2023 Nov;
6(1):1165.
PMID: 37963972
In arterial myocytes, the canonical function of voltage-gated Ca1.2 and K2.1 channels is to induce myocyte contraction and relaxation through their responses to membrane depolarization, respectively. Paradoxically, K2.1 also plays...
3.
Matsumoto C, ODwyer S, Manning D, Hernandez-Hernandez G, Rhana P, Fong Z, et al.
Res Sq
. 2023 Jul;
PMID: 37502980
In arterial myocytes, the canonical function of voltage-gated Ca1.2 and K2.1 channels is to induce myocyte contraction and relaxation through their responses to membrane depolarization, respectively. Paradoxically, K2.1 also plays...
4.
Matsumoto C, ODwyer S, Manning D, Hernandez-Hernandez G, Rhana P, Fong Z, et al.
bioRxiv
. 2023 Jul;
PMID: 37425816
In arterial myocytes, the canonical function of voltage-gated Ca 1.2 and K 2.1 channels is to induce myocyte contraction and relaxation through their responses to membrane depolarization, respectively. Paradoxically, K...
5.
Durco A, Souza D, Rhana P, Costa A, Marques L, Santos L, et al.
Toxicol Appl Pharmacol
. 2023 Jul;
474:116609.
PMID: 37392997
Background: Arrhythmias are one manifestation of the cardiotoxicity that results from doxorubicin (Doxo) administration. Although cardiotoxicity is an anticipated outcome in anticancer therapies, there is still a lack of treatment...
6.
Lillo M, Munoz M, Rhana P, Gaul-Muller K, Quan J, Shirokova N, et al.
J Gen Physiol
. 2023 May;
155(7).
PMID: 37191672
Connexin-43 (Cx43) is the most abundant protein forming gap junction channels (GJCs) in cardiac ventricles. In multiple cardiac pathologies, including hypertrophy and heart failure, Cx43 is found remodeled at the...
7.
Souza D, Marques L, Costa A, Cruz J, Rhana P, Santos-Miranda A, et al.
Life Sci
. 2022 Sep;
308:120945.
PMID: 36096245
Aims: Hypothyroidism is associated with an increased risk of cardiovascular disease and enhanced susceptibility to arrhythmias. In our investigation, we evaluated the potential involvement of late sodium current (I) in...
8.
Rhana P, Barros G, Santos V, Costa A, Dos Santos D, Fernandes-Braga W, et al.
Eur J Pharmacol
. 2022 Jul;
930:175134.
PMID: 35843301
Background: Myocardial infarction (MI) is associated with high mortality rates, despite the fact that there are therapies available. Importantly, excessive oxidative stress may contribute to ischemia/reperfusion injury leading to death...
9.
Santos-Miranda A, Costa A, Joviano-Santos J, Rhana P, Bruno A, Rocha P, et al.
FASEB J
. 2021 Sep;
35(10):e21901.
PMID: 34569665
Chagasic cardiomyopathy (CCC) is one of the main causes of heart failure and sudden death in Latin America. To date, there is no available medication to prevent or reverse the...
10.
Elasoru S, Rhana P, de Oliveira Barreto T, Naves de Souza D, Menezes-Filho J, Souza D, et al.
Eur J Pharmacol
. 2021 May;
906:174194.
PMID: 34044012
Myocardial infarction (MI) is the irreversible injury of the myocardium caused by prolonged myocardial ischemia and is a major cause of heart failure and eventual death among ischemic patients. The...