Paula Ossowicz-Rupniewska
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Explore the profile of Paula Ossowicz-Rupniewska including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
157
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Recent Articles
1.
Peruzynska M, Nowak A, Muzykiewicz-Szymanska A, Kucharski L, Klebeko J, Bilska K, et al.
Pharmacol Rep
. 2024 Oct;
76(6):1470-1481.
PMID: 39425885
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for pain relief and inflammation management, but there are challenges related to poor solubility and bioavailability. We explored modifications of ibuprofen (IBU) by...
2.
Kopciuch E, Janus E, Ossowicz-Rupniewska P, Nowak A, Duchnik W, Kucharski L, et al.
Eur J Pharm Biopharm
. 2024 Sep;
204:114505.
PMID: 39306198
In the study, the modification of naproxen (NAP) with esters of four amino acids (AAs): glycine (GlyOiPr), L-proline (ProOiPr), L-leucine (LeuOiPr), and L-serine (SerOiPr) isopropyl ester was performed to improve...
3.
Zyburtowicz K, Bednarczyk P, Nowak A, Muzykiewicz-Szymanska A, Kucharski L, Wesolowska A, et al.
Int J Mol Sci
. 2024 Jun;
25(11).
PMID: 38892359
Transdermal drug delivery offers a promising alternative for administering medications like ibuprofen, known for its analgesic and anti-inflammatory properties, with reduced gastrointestinal side effects compared to oral administration. This study...
4.
Ossowicz-Rupniewska P, Klebeko J, Georgieva I, Apostolova S, Struk L, Todinova S, et al.
Pharmaceutics
. 2024 Apr;
16(4).
PMID: 38675157
Betulinic acid (BA) is a natural pentacyclic triterpene with diverse biological activities. However, its low water solubility limits its pharmaceutical application. The conversion of pharmaceutically active molecules into ionic liquids...
5.
Witkowski K, Nowak A, Duchnik W, Kucharski L, Struk L, Ossowicz-Rupniewska P
Molecules
. 2023 Nov;
28(22).
PMID: 38005244
This research presents novel ibuprofen derivatives in the form of alkyl ester salts of L-amino acids with potential analgesic, anti-inflammatory, and antipyretic properties for potential use in transdermal therapeutic systems....
6.
Bednarczyk P, Nowak A, Duchnik W, Kucharski L, Ossowicz-Rupniewska P
Int J Mol Sci
. 2023 Nov;
24(21).
PMID: 37958615
This study investigated the impact of various enhancers on permeation through the skin and accumulation in the skin from acrylic pressure-sensitive adhesive-based drug-in-adhesives matrix-type transdermal patches. Eleven patches, each containing...
7.
Adamiak-Giera U, Nowak A, Duchnik W, Ossowicz-Rupniewska P, Czerkawska A, Machoy-Mokrzynska A, et al.
Front Pharmacol
. 2023 Jun;
14:1157977.
PMID: 37324484
In the treatment of pain, especially chronic pain, the rule of multimodal therapy applies, based on various painkillers mechanisms of action. The aim of the conducted study was to evaluate...
8.
Agboola A, Nowak A, Duchnik W, Kucharski L, Story A, Story G, et al.
Gels
. 2023 May;
9(5).
PMID: 37232983
The aim of this study was to evaluate the effect of vehicle and chemical modifications of the structure of active compounds on the skin permeation and accumulation of ibuprofen (IBU)....
9.
Ossowicz-Rupniewska P, Nowak A, Konopacki M, Kordas M, Kucharski L, Klebeko J, et al.
Eur J Pharm Biopharm
. 2023 May;
188:15-25.
PMID: 37164233
A method of increasing the permeability of ibuprofen through the skin using a rotating magnetic field (RMF) is presented. This study evaluated whether 50 Hz RMF modifies ibuprofen's permeability through...
10.
Rakoczy R, Nowak A, Konopacki M, Kordas M, Kucharski L, Ossowicz-Rupniewska P
Eur J Pharm Biopharm
. 2023 Mar;
185:183-189.
PMID: 36905969
The paper presents a method of increasing the permeability of various active substances through the skin by means of a rotating magnetic field. The study used 50 Hz RMF and...