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Paul Wei-Che Hsu

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Articles 27
Citations 1105
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Recent Articles
1.
Hsu P, Chen Y, Sheu W
J Diabetes Investig . 2025 Feb; PMID: 39945407
Aims: Current metabolic syndrome (mets) criteria often lack consideration for age and gender differences. This study introduces the mets-Z score, a novel tool designed to enhance mets assessment and improve...
2.
Lu S, Wu Y, Su L, Hsu Z, Weng T, Wang H, et al.
Stem Cell Reports . 2023 Jun; 18(7):1405-1420. PMID: 37295424
Sarcomeres are fundamental to cardiac muscle contraction. Their impairment can elicit cardiomyopathies, leading causes of death worldwide. However, the molecular mechanism underlying sarcomere assembly remains obscure. We used human embryonic...
3.
Wu I, Tsai T, Lo C, Chou Y, Yeh C, Chan Y, et al.
NPJ Digit Med . 2022 Nov; 5(1):166. PMID: 36323795
Diabetic kidney disease is the leading cause of end-stage kidney disease worldwide; however, the integration of high-dimensional trans-omics data to predict this diabetic complication is rare. We develop artificial intelligence...
4.
Hsu P, Liao P, Kao Y, Lin X, Chien R, Yeh C, et al.
Int J Mol Sci . 2022 Oct; 23(20). PMID: 36293566
Gilbert's syndrome is mainly diagnosed through genetic analysis and is primarily detected through a mutation in the promoter region of the gene. However, most of the research has been conducted...
5.
Shyu Y, Liao P, Huang T, Yang C, Lu M, Huang S, et al.
Adv Sci (Weinh) . 2022 Jul; 9(25):e2201409. PMID: 35822667
The quest for rejuvenation and prolonged lifespan through transfusion of young blood has been studied for decades with the hope of unlocking the mystery of the key substance(s) that exists...
6.
Yeh C, Chou Y, Tsai T, Hsu P, Li C, Chan Y, et al.
Biomedicines . 2022 Jan; 10(1). PMID: 35052795
An increased risk of cardiovascular events was identified in patients with peripheral artery disease (PAD). Clopidogrel is one of the most widely used antiplatelet medications. However, there are heterogeneous outcomes...
7.
Lu S, Lee K, Hsu P, Su L, Yeh Y, Pan C, et al.
Circ Res . 2021 Nov; 130(1):112-129. PMID: 34816743
Background: Mutations in genes encoding sarcomeric proteins lead to failures in sarcomere assembly, the building blocks of contracting muscles, resulting in cardiomyopathies that are a leading cause of morbidity and...
8.
Yang N, Yeh C, Tsai T, Chou Y, Hsu P, Li C, et al.
Cells . 2021 Sep; 10(9). PMID: 34572079
Heart failure (HF) is a global pandemic public health burden affecting one in five of the general population in their lifetime. For high-risk individuals, early detection and prediction of HF...
9.
Yeh C, Huang W, Hsu P, Yeh K, Wang L, Hsu P, et al.
EMBO J . 2021 Jan; 40(7):e105846. PMID: 33469951
Protein termini are determinants of protein stability. Proteins bearing degradation signals, or degrons, at their amino- or carboxyl-termini are eliminated by the N- or C-degron pathways, respectively. We aimed to...
10.
Lee S, Hwang H, Hsu P, Chuang T, Liu C, Wu L
Genomics . 2018 Sep; 111(6):1381-1386. PMID: 30248490
Identifying heterogeneity in chronic obstructive pulmonary disease (COPD) phenotypes is important for the development of personalized medicine. Genome-wide analysis was used to compare the methylation levels of peripheral blood mononuclear...