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Paul Walther

Explore the profile of Paul Walther including associated specialties, affiliations and a list of published articles. Areas
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Articles 162
Citations 4966
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Recent Articles
1.
Olari L, Liu S, Arnold F, Kuhlwein J, Gil Miro M, Updahaya A, et al.
Nat Commun . 2025 Jan; 16(1):813. PMID: 39827271
HIV-associated neurocognitive disorders (HAND) and viral reservoirs in the brain remain a significant challenge. Despite their importance, the mechanisms allowing HIV-1 entry and replication in the central nervous system (CNS)...
2.
Rauch-Wirth L, Schutz D, Gross R, Rode S, Glocker B, Muller J, et al.
Biomaterials . 2025 Jan; 317:123044. PMID: 39754968
Retroviral gene transfer is the preferred method for stable, long-term integration of genetic material into cellular genomes, commonly used to generate chimeric antigen receptor (CAR)-T cells designed to target tumor...
3.
Wieland J, Naskar N, Reess K, Dos Santos D, Weise J, Blatt T, et al.
Front Biosci (Landmark Ed) . 2024 Nov; 29(11):383. PMID: 39614446
Background: Coenzyme Q (CoQ), also known as ubiquinone-10, is an important molecule of the mitochondrial respiratory chain that acts as an electron carrier between complexes I, II, and III and...
4.
Mook A, Herzog J, Walther P, Durre P, Bengelsdorf F
Microb Cell Fact . 2024 Jul; 23(1):213. PMID: 39061103
Background: Acetogens, a diverse group of anaerobic autotrophic bacteria, are promising whole-cell biocatalysts that fix CO during their growth. However, because of energetic constraints, acetogens exhibit slow growth and the...
5.
Volcic M, Nchioua R, Pastorio C, Zech F, Haussmann I, Sauter D, et al.
J Med Virol . 2024 Jul; 96(7):e29783. PMID: 38965890
Many COVID-19 patients suffer from gastrointestinal symptoms and impaired intestinal barrier function is thought to play a key role in Long COVID. Despite its importance, the impact of severe acute...
6.
Enzenmuller S, Niedermayer A, Seyfried F, Muench V, Tews D, Rupp U, et al.
Cell Death Dis . 2024 Jul; 15(7):475. PMID: 38961053
Deregulated apoptosis signaling is characteristic for many cancers and contributes to leukemogenesis and treatment failure in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Apoptosis is controlled by different pro- and anti-apoptotic...
7.
Vitasovic T, Caniglia G, Eghtesadi N, Ceccato M, Bo Jesen E, Gosewinkel U, et al.
ACS Appl Mater Interfaces . 2024 Jun; 16(24):30847-30859. PMID: 38853353
Antibacterial formulations based on zinc oxide nanoparticles (ZnO NPs) are widely used for antibiotic replacement in veterinary medicine and animal nutrition. However, the undesired environmental impact of ZnO NPs triggers...
8.
Bizjak D, Ohmayer B, Buhl J, Schneider E, Walther P, Calzia E, et al.
Int J Mol Sci . 2024 Feb; 25(3). PMID: 38338957
Patients suffering from chronic fatigue syndrome (CFS) or post-COVID syndrome (PCS) exhibit a reduced physiological performance capability. Impaired mitochondrial function and morphology may play a pivotal role. Thus, we aimed...
9.
Hirschenberger M, Lepelley A, Rupp U, Klute S, Hunszinger V, Koepke L, et al.
Nat Commun . 2023 Nov; 14(1):6770. PMID: 37914730
Type I interferon (IFN) signalling is tightly controlled. Upon recognition of DNA by cyclic GMP-AMP synthase (cGAS), stimulator of interferon genes (STING) translocates along the endoplasmic reticulum (ER)-Golgi axis to...
10.
Olari L, Bauer R, Gil Miro M, Vogel V, Cortez Rayas L, Gross R, et al.
Cell Mol Life Sci . 2023 May; 80(6):151. PMID: 37198527
Antimicrobial peptides (AMPs) are major components of the innate immune defense. Accumulating evidence suggests that the antibacterial activity of many AMPs is dependent on the formation of amyloid-like fibrils. To...