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Paul V Harris

Explore the profile of Paul V Harris including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 531
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Recent Articles
1.
Kim I, Seo N, An H, Kim J, Harris P, Kim K
Biotechnol Biofuels . 2017 Mar; 10:46. PMID: 28250814
Background: Lytic polysaccharide monooxygenase (LPMO) is a group of recently identified proteins that catalyze oxidative cleavage of the glycosidic linkages of cellulose and other polysaccharides. By utilizing the oxidative mode...
2.
Agirre J, Ariza A, Offen W, Turkenburg J, Roberts S, McNicholas S, et al.
Acta Crystallogr D Struct Biol . 2016 Feb; 72(Pt 2):254-65. PMID: 26894673
The industrial conversion of cellulosic plant biomass into useful products such as biofuels is a major societal goal. These technologies harness diverse plant degrading enzymes, classical exo- and endo-acting cellulases...
3.
Moroz O, Maranta M, Shaghasi T, Harris P, Wilson K, Davies G
Acta Crystallogr F Struct Biol Commun . 2015 Jan; 71(Pt 1):114-20. PMID: 25615982
The enzymatic degradation of plant cell-wall cellulose is central to many industrial processes, including second-generation biofuel production. Key players in this deconstruction are the fungal cellobiohydrolases (CBHs), notably those from...
4.
Lo Leggio L, Simmons T, Poulsen J, Frandsen K, Hemsworth G, Stringer M, et al.
Nat Commun . 2015 Jan; 6:5961. PMID: 25608804
Lytic polysaccharide monooxygenases (LPMOs) are recently discovered enzymes that oxidatively deconstruct polysaccharides. LPMOs are fundamental in the effective utilization of these substrates by bacteria and fungi; moreover, the enzymes have...
5.
Harris P, Xu F, Kreel N, Kang C, Fukuyama S
Curr Opin Chem Biol . 2014 Apr; 19:162-70. PMID: 24681544
Innovations at a small scale through enzyme discovery in the laboratory can have large scale impacts when rolled out in an industrial process, and this is evidenced in recent advances...
6.
Harris P, Welner D, McFarland K, Re E, Poulsen J, Brown K, et al.
Biochemistry . 2010 Mar; 49(15):3305-16. PMID: 20230050
Currently, the relatively high cost of enzymes such as glycoside hydrolases that catalyze cellulose hydrolysis represents a barrier to commercialization of a biorefinery capable of producing renewable transportable fuels such...
7.
M Krogh K, Harris P, Olsen C, Johansen K, Hojer-Pedersen J, Borjesson J, et al.
Appl Microbiol Biotechnol . 2009 Sep; 86(1):143-54. PMID: 19756584
A GH3 beta-glucosidase (BGL) from Penicillium brasilianum was purified to homogeneity after cultivation on a cellulose and xylan rich medium. The BGL was identified in a genomic library, and it...
8.
Kim K, Brown K, Harris P, Langston J, Cherry J
J Proteome Res . 2007 Nov; 6(12):4749-57. PMID: 18020405
Economically competitive production of ethanol from lignocellulosic biomass by enzymatic hydrolysis and fermentation is currently limited, in part, by the relatively high cost and low efficiency of the enzymes required...