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Paul S Knoepfler

Explore the profile of Paul S Knoepfler including associated specialties, affiliations and a list of published articles. Areas
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Articles 67
Citations 2713
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Recent Articles
21.
Chen K, Knoepfler P
Regen Med . 2016 Dec; 11(8):801-816. PMID: 27905217
The goal of editing the genomes of stem cells to generate model organisms and cell lines for genetic and biological studies has been pursued for decades. There is also exciting...
22.
Knoepfler P
Nat Med . 2016 Mar; 22(3):230. PMID: 26937614
No abstract available.
23.
Knoepfler P
Adv Drug Deliv Rev . 2014 Dec; 82-83:192-6. PMID: 25489841
The phrase "bench-to-bedside" is commonly used to describe the translation of basic discoveries such as those on stem cells to the clinic for therapeutic use in human patients. However, there...
24.
Yuen B, Bush K, Barrilleaux B, Cotterman R, Knoepfler P
Development . 2014 Aug; 141(18):3483-94. PMID: 25142466
The histone variant H3.3 is involved in diverse biological processes, including development, transcriptional memory and transcriptional reprogramming, as well as diseases, including most notably malignant brain tumors. Recently, we developed...
25.
Barrilleaux B, Burow D, Lockwood S, Yu A, Segal D, Knoepfler P
PLoS One . 2014 Jul; 9(7):e101151. PMID: 24983942
The transcription factor Miz-1 can either activate or repress gene expression in concert with binding partners including the Myc oncoprotein. The genomic binding of Miz-1 includes both core promoters and...
26.
Yuen B, Knoepfler P
Cancer Cell . 2013 Nov; 24(5):567-74. PMID: 24229707
A host of cancer types exhibit aberrant histone modifications. Recently, distinct and recurrent mutations in a specific histone variant, histone H3.3, have been implicated in a high proportion of malignant...
27.
Knoepfler P
Stem Cells Dev . 2013 Oct; 22 Suppl 1:10-2. PMID: 24147571
The stem cell field is at a critical juncture in late 2013. We find ourselves buoyed by building momentum for both transformative basic science discoveries and clinical translation of stem...
28.
Knoepfler P
Nat Med . 2013 Sep; 19(9):1086. PMID: 24013741
No abstract available.
29.
Barrilleaux B, Cotterman R, Knoepfler P
Methods Mol Biol . 2013 Sep; 1012:117-33. PMID: 24006062
Myc and N-Myc have widespread impacts on the chromatin state within cells, both in a gene-specific and genome-wide manner. Our laboratory uses functional genomic methods including chromatin immunoprecipitation (ChIP), ChIP-chip,...
30.
Tung P, Varlakhanova N, Knoepfler P
Stem Cells . 2013 Aug; 31(11):2330-42. PMID: 23963736
In order to identify novel pluripotency-related oncogenes, an expression screen for oncogenic foci-inducing genes within a retroviral human embryonic stem cell cDNA library was conducted. From this screen, we identified...