Paul S Knoepfler
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Explore the profile of Paul S Knoepfler including associated specialties, affiliations and a list of published articles.
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2713
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Recent Articles
11.
Chen K, Bush K, Klein R, Cervantes V, Lewis N, Naqvi A, et al.
Commun Biol
. 2020 Jul;
3(1):363.
PMID: 32647372
Histone H3.3 mutations are a hallmark of pediatric gliomas, but their core oncogenic mechanisms are not well-defined. To identify major effectors, we used CRISPR-Cas9 to introduce H3.3K27M and G34R mutations...
12.
Knoepfler P
Regen Med
. 2019 Aug;
14(8):735-740.
PMID: 31456478
The industry of unproven stem cell clinics has rapidly mushroomed throughout the USA, posing risks to patients and the research field. In this study, the aim was to better define...
13.
Knoepfler P
Regen Med
. 2018 Oct;
13(7):845-858.
PMID: 30289055
The stem cell and regenerative medicine arena has become increasingly complicated in recent years with thousands of people involved. There are as many as a dozen or more main groups...
14.
Klein R, Tung P, Somanath P, Fehling H, Knoepfler P
Stem Cell Res
. 2018 Jul;
31:83-94.
PMID: 30031967
Developmental pluripotency associated factor 4 (Dppa4) is a highly specific marker of pluripotent cells, and is also overexpressed in certain cancers, but its function in either of these contexts is...
15.
Knoepfler P
Cell Stem Cell
. 2018 Jun;
23(1):18-20.
PMID: 29937201
Regulators are now more often distinguishing between perceived good citizens and "bad actors" in stem cell and regenerative medicine clinical research, resulting in relatively more polar, carrot-and-stick oversight approaches. Here,...
16.
Knoepfler P, Turner L
Regen Med
. 2018 Jan;
13(1):19-27.
PMID: 29327974
Hundreds of businesses in the US currently advertise a wide range of non-US FDA-approved stem cell interventions. Here we present a novel systematic temporal analysis of US companies engaged in...
17.
Somanath P, Bush K, Knoepfler P
Stem Cells
. 2018 Jan;
36(5):671-682.
PMID: 29327467
Developmental Pluripotency-Associated-4 (DPPA4) is one of the few core pluripotency genes lacking clearly defined molecular and cellular functions. Here, we used a proteomics screening approach of human embryonic stem cell...
18.
Somanath P, Klein R, Knoepfler P
PLoS One
. 2017 Oct;
12(10):e0185627.
PMID: 28982113
The transcriptional functions of the class I histone deacetylases (HDACs) HDAC1 and HDAC2 are mainly viewed as both repressive and redundant based on murine knockout studies, but they may have...
19.
Martinez-Cerdeno V, Barrilleaux B, McDonough A, Ariza J, Yuen B, Somanath P, et al.
Stem Cells Dev
. 2017 Jul;
26(19):1409-1423.
PMID: 28693365
Human pluripotent stem cells (hPSC) have great clinical potential through the use of their differentiated progeny, a population in which there is some concern over risks of tumorigenicity or other...
20.
Knoepfler P
Stem Cells Transl Med
. 2017 Feb;
6(1):14-16.
PMID: 28170181
The growing direct-to-consumer, stem cell clinic industry in the U.S. uses a number of strategies for patient recruitment, including self-styled educational seminars, which may reach thousands of members of the...