Paul Roschger
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Explore the profile of Paul Roschger including associated specialties, affiliations and a list of published articles.
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136
Citations
2467
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Recent Articles
1.
Blouin S, Khani F, Messmer P, Roschger P, Hartmann M, van Wijnen A, et al.
J Bone Miner Res
. 2023 Jul;
38(10):1509-1520.
PMID: 37493605
Vitamin C (VitC) is essential for bone health, and low VitC serum levels increase the risk for skeletal fractures. If and how VitC affects bone mineralization is unclear. Using micro-computed...
2.
Blouin S, Misof B, Mahr M, Fratzl-Zelman N, Roschger P, Lueger S, et al.
Acta Biomater
. 2022 Dec;
157:275-287.
PMID: 36549635
Osteocytes act as bone mechanosensors, regulators of osteoblast/osteoclast activity and mineral homeostasis, however, knowledge about their functional/morphological changes throughout life is limited. We used quantitative backscattered electron imaging (qBEI) to...
3.
Misof B, Roschger P, Mahr M, Fratzl-Zelman N, Glorieux F, Hartmann M, et al.
Bone
. 2022 Oct;
166:116580.
PMID: 36210024
No abstract available.
4.
Misof B, Blouin S, Andrade V, Roschger P, Borba V, Hartmann M, et al.
J Musculoskelet Neuronal Interact
. 2022 Sep;
22(3):305-315.
PMID: 36046986
Objectives: Patients with type-2 diabetes mellitus (T2DM) have increased risk for bone fractures which points towards impaired bone quality. Methods: We measured bone mineralization density distribution (BMDD) and osteocyte lacunae...
5.
Hofstaetter J, Atkins G, Kato H, Kogawa M, Blouin S, Misof B, et al.
Calcif Tissue Int
. 2022 May;
111(4):430-444.
PMID: 35618777
Osteopetrosis is a heterogeneous group of rare hereditary diseases characterized by increased bone mass of poor quality. Autosomal-dominant osteopetrosis type II (ADOII) is most often caused by mutation of the...
6.
Lui J, Raimann A, Hojo H, Dong L, Roschger P, Kikani B, et al.
Nat Commun
. 2022 Feb;
13(1):700.
PMID: 35121733
SP7/Osterix is a transcription factor critical for osteoblast maturation and bone formation. Homozygous loss-of-function mutations in SP7 cause osteogenesis imperfecta type XII, but neomorphic (gain-of-new-function) mutations of SP7 have not...
7.
Tang C, Castro Andrade C, OMeara M, Yoon S, Sato T, Brooks D, et al.
Elife
. 2021 Jun;
10.
PMID: 34160349
Bone formation and resorption are typically coupled, such that the efficacy of anabolic osteoporosis treatments may be limited by bone destruction. The multi-kinase inhibitor YKL-05-099 potently inhibits salt inducible kinases...
8.
Al Kaissi A, Misof B, Laccone F, Blouin S, Roschger P, Kircher S, et al.
Calcif Tissue Int
. 2021 May;
109(5):586-595.
PMID: 34003338
Proteus syndrome is a rare genetic disorder, which is characterized by progressive, segmental, or patchy overgrowth of diverse tissues of all germ layers, including the skeleton. Here, we present a...
9.
Ayoubi M, van Tol A, Weinkamer R, Roschger P, Brugger P, Berzlanovich A, et al.
Adv Healthc Mater
. 2021 May;
10(12):e2100113.
PMID: 33963821
During bone remodeling, osteoblasts are known to deposit unmineralized collagenous tissue (osteoid), which mineralizes after some time lag. Some of the osteoblasts differentiate into osteocytes, forming a cell network within...
10.
Kuroda Y, Kawaai K, Hatano N, Wu Y, Takano H, Momose A, et al.
J Bone Miner Res
. 2021 Apr;
36(8):1535-1547.
PMID: 33905562
Auditory ossicles in the middle ear and bony labyrinth of the inner ear are highly mineralized in adult mammals. Cellular mechanisms underlying formation of dense bone during development are unknown....