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Paul R Grant

Explore the profile of Paul R Grant including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 420
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Recent Articles
1.
Botha J, Byott M, Spyer M, Grant P, Gartner K, Chen W, et al.
Viruses . 2023 Sep; 15(9). PMID: 37766218
Modern HIV-1 treatment effectively suppresses viral amplification in people living with HIV. However, the persistence of HIV-1 DNA as proviruses integrated into the human genome remains the main barrier to...
2.
Buck M, Poirier E, Cardoso A, Frederico B, Canton J, Barrell S, et al.
Wellcome Open Res . 2021 Jun; 6:9. PMID: 34095506
The ongoing pandemic of SARS-CoV-2 calls for rapid and cost-effective methods to accurately identify infected individuals. The vast majority of patient samples is assessed for viral RNA presence by RT-qPCR....
3.
Aitken J, Ambrose K, Barrell S, Beale R, Bineva-Todd G, Biswas D, et al.
Nat Biotechnol . 2020 Jul; 38(8):1000. PMID: 32681136
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
4.
Aitken J, Ambrose K, Barrell S, Beale R, Bineva-Todd G, Biswas D, et al.
Nat Biotechnol . 2020 Jun; 38(8):927-931. PMID: 32555528
No abstract available.
5.
Busby E, Whale A, Ferns R, Grant P, Morley G, Campbell J, et al.
Sci Rep . 2017 Apr; 7(1):1209. PMID: 28446770
Establishing a cure for HIV is hindered by the persistence of latently infected cells which constitute the viral reservoir. Real-time qPCR, used for quantification of this reservoir by measuring HIV...
6.
Jones G, Busby E, Garson J, Grant P, Nastouli E, Devonshire A, et al.
Biomol Detect Quantif . 2016 Dec; 10:31-33. PMID: 27990347
Digital PCR (dPCR) has been reported to be more precise and sensitive than real-time quantitative PCR (qPCR) in a variety of models and applications. However, in the majority of commercially...
7.
Arora N, Schuenemann V, Jager G, Peltzer A, Seitz A, Herbig A, et al.
Nat Microbiol . 2016 Dec; 2:16245. PMID: 27918528
The abrupt onslaught of the syphilis pandemic that started in the late fifteenth century established this devastating infectious disease as one of the most feared in human history. Surprisingly, despite...
8.
Whale A, Bushell C, Grant P, Cowen S, Gutierrez-Aguirre I, OSullivan D, et al.
J Clin Microbiol . 2015 Dec; 54(2):392-400. PMID: 26659206
Digital PCR (dPCR) is being increasingly used for the quantification of sequence variations, including single nucleotide polymorphisms (SNPs), due to its high accuracy and precision in comparison with techniques such...
9.
Smith N, Mlcochova P, Watters S, Aasa-Chapman M, Rabin N, Moore S, et al.
Clin Infect Dis . 2015 Mar; 61(1):120-8. PMID: 25778749
Background: Emerging data relating to human immunodeficiency virus type 1 (HIV-1) cure suggest that vaccination to stimulate the host immune response, particularly cytotoxic cells, may be critical to clearing of...
10.
Garson J, Ferns R, Grant P, Ijaz S, Nastouli E, Szypulska R, et al.
J Virol Methods . 2012 Aug; 186(1-2):157-60. PMID: 22871672
Hepatitis E virus (HEV) is a major cause of acute viral hepatitis in many parts of the developing world. It is responsible for both sporadic infections and large scale epidemics...