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Paul Potter

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Articles 32
Citations 830
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Recent Articles
1.
Kooblall K, Stevenson M, Stewart M, Harris L, Zalucki O, Dewhurst H, et al.
JBMR Plus . 2023 Jun; 7(6):e10739. PMID: 37283649
The nuclear factor I/X () gene encodes a ubiquitously expressed transcription factor whose mutations lead to two allelic disorders characterized by developmental, skeletal, and neural abnormalities, namely, Malan syndrome (MAL)...
2.
Khalil Y, Carrino S, Lin F, Ferlin A, Lad H, Mazzacuva F, et al.
Int J Mol Sci . 2022 Jan; 23(2). PMID: 35055171
Peroxisomal fatty acid α-oxidation is an essential pathway for the degradation of β-carbon methylated fatty acids such as phytanic acid. One enzyme in this pathway is 2-hydroxyacyl CoA lyase (HACL1),...
3.
Randles M, Lausecker F, Kong Q, Suleiman H, Reid G, Kolatsi-Joannou M, et al.
J Am Soc Nephrol . 2021 May; 32(7):1713-1732. PMID: 34049963
Background: Accumulation of extracellular matrix in organs and tissues is a feature of both aging and disease. In the kidney, glomerulosclerosis and tubulointerstitial fibrosis accompany the decline in function, which...
4.
Wentzel N, Panieri A, Ayazi M, Ntshalintshali S, Pourpak Z, Hawarden D, et al.
World Allergy Organ J . 2019 Oct; 12(9):100049. PMID: 31641402
Background: International guideline-recommended on-demand treatments for hereditary angioedema (HAE) include: C1-esterase inhibitor (plasma-derived or recombinant), or bradykinin-receptor antagonists. In most low- and middle-income countries (LMIC) these products are not registered...
5.
Schosserer M, Banks G, Dogan S, Dungel P, Fernandes A, Marolt Presen D, et al.
Mech Ageing Dev . 2018 Oct; 177:91-102. PMID: 30290161
Geroprotectors, a class of drugs targeting multiple deficits occurring with age, necessitate the development of new animal models to test their efficacy. The COST Action MouseAGE is a European network...
6.
Bousquet J, Hellings P, Agache I, Amat F, Annesi-Maesano I, Ansotegui I, et al.
J Allergy Clin Immunol . 2018 Oct; 143(3):864-879. PMID: 30273709
Allergic Rhinitis and its Impact on Asthma (ARIA) has evolved from a guideline by using the best approach to integrated care pathways using mobile technology in patients with allergic rhinitis...
7.
Santamaria E, Izquierdo I, Valle M, Vermeulen J, Potter P
J Asthma Allergy . 2018 Sep; 11:225-231. PMID: 30214250
Background: There are few clinical trials that assess the efficacy of antihistamines in very young children. Rupatadine is a second-generation antihistamine indicated for the treatment of allergic rhinitis (AR) and...
8.
Curley M, Milne L, Smith S, Jorgensen A, Frederiksen H, Hadoke P, et al.
FASEB J . 2018 Aug; 33(1):978-995. PMID: 30080443
Testicular Leydig cells (LCs) are the primary source of circulating androgen in men. As men age, circulating androgen levels decline. However, whether reduced LC steroidogenesis results from specific effects of...
9.
Koks S, Dogan S, Guvenc Tuna B, Gonzalez-Navarro H, Potter P, Vandenbroucke R
Mech Ageing Dev . 2016 Oct; 160:41-53. PMID: 27717883
Ageing is a process that gradually increases the organism's vulnerability to death. It affects different biological pathways, and the underlying cellular mechanisms are complex. In view of the growing disease...
10.
Jackson S, Andrews N, Ball D, Bellantuono I, Gray J, Hachoumi L, et al.
Lab Anim . 2016 Jun; 51(2):160-169. PMID: 27307423
Rodent models produce data which underpin biomedical research and non-clinical drug trials, but translation from rodents into successful clinical outcomes is often lacking. There is a growing body of evidence...