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Paul Lochhead

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Articles 90
Citations 5516
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Recent Articles
1.
Lopes E, Boneschansker L, Chu J, Ha J, Badran Y, Diaz P, et al.
Gastro Hep Adv . 2023 Dec; 2(8):1082-1087. PMID: 38088988
Background And Aims: Informed consent should allow patients the appropriate time and conditions to make decisions about their care. However, consent is often obtained immediately prior to a colonoscopy. We...
2.
Sun J, Halfvarson J, Bergman D, Ebrahimi F, Roelstraete B, Lochhead P, et al.
EClinicalMedicine . 2023 Sep; 63:102182. PMID: 37662517
Background: Statin use has been linked to a reduced risk of advanced colorectal adenomas, but its association with colorectal cancer (CRC) in patients with inflammatory bowel disease (IBD) - a...
3.
Sharma R, Simon T, Hagstrom H, Lochhead P, Roelstraete B, Soderling J, et al.
Clin Gastroenterol Hepatol . 2023 Apr; 22(4):749-759.e19. PMID: 37121528
Background & Aims: Little is known about the potential impact of statins on the progression of noncirrhotic chronic liver diseases (CLDs) to severe liver disease. Methods: Using liver histopathology data...
4.
Lopes E, Chan S, Song M, Ludvigsson J, Hakansson N, Lochhead P, et al.
Gut . 2023 Jan; PMID: 36591609
Objective: To estimate the proportion of cases of Crohn's disease (CD) and ulcerative colitis (UC) that could be prevented by modifiable lifestyle factors. Design: In a prospective cohort study of...
5.
Lo C, Ni P, Yan Y, Ma W, Joshi A, Nguyen L, et al.
Gastroenterology . 2022 Jul; 163(4):852-861.e2. PMID: 35788344
Background & Aims: The use of proton pump inhibitors (PPIs) has increased rapidly in the past 2 decades. Concerns about the regular use of PPIs contributing to mortality have been...
6.
Mehta R, Lochhead P, Wang Y, Ma W, Nguyen L, Kochar B, et al.
PLoS One . 2022 Mar; 17(3):e0264649. PMID: 35320274
The gut microbiome is increasingly recognized to play a role in cognition and dementia. Antibiotic use impacts the gut microbiome and has been linked with chronic disease. Despite these data,...
7.
Hua X, Lopes E, Burke K, Ananthakrishnan A, Richter J, Lo C, et al.
J Crohns Colitis . 2022 Feb; 16(7):1030-1038. PMID: 35102373
Background And Aims: We examined smoking behaviour changes after diagnoses of Crohn's disease [CD] and ulcerative colitis [UC] and evaluated their impact on mortality. Methods: Study population included incident CD...
8.
Lopes E, Lochhead P, Burke K, Richter J, Ananthakrishnan A, Chan A, et al.
Clin Gastroenterol Hepatol . 2022 Jan; 20(10):2347-2357.e14. PMID: 35031525
Background & Aims: We examined whether relationships between known risk factors for Crohn's disease (CD) and ulcerative colitis (UC) differ according to disease phenotype, defined by Montreal classification, at the...
9.
Casey K, Lopes E, Niccum B, Burke K, Ananthakrishnan A, Lochhead P, et al.
Aliment Pharmacol Ther . 2021 Dec; 55(2):225-233. PMID: 34881819
Background And Aims: There are limited data on alcohol dose and types and risk of Crohn's Disease (CD) and Ulcerative Colitis (UC). We therefore sought to comprehensively examine the association...
10.
Lochhead P, Khalili H, Ananthakrishnan A, Burke K, Richter J, Sun Q, et al.
Environ Res . 2021 Oct; 207:112222. PMID: 34662575
Background: Perfluoroalkyl substances (PFASs) are synthetic compounds used in a wide variety of industrial and consumer applications. An association between PFAS exposure and risk of ulcerative colitis (UC) has been...