Paul Kumaran
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Explore the profile of Paul Kumaran including associated specialties, affiliations and a list of published articles.
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27
Citations
507
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Recent Articles
1.
Giridharan P, Murugesan H, Selvaraju S, Frederick A, Selvavinayagam T, Nagarajan K, et al.
Glob Health Sci Pract
. 2024 Jan;
12(1).
PMID: 38272679
Estimating the burden of TB at the subnational level is critical to planning and prioritizing resources for TB control activities according to the local epidemiological situation. We report the experiences...
2.
Kathamuthu G, Kumar N, Moideen K, Dolla C, Kumaran P, Babu S
Pathogens
. 2022 Jan;
11(1).
PMID: 35056035
Mucosal-associated invariant T (MAIT) cells are innate like, and play a major role in restricting disease caused by (Mtb) disease before the activation of antigen-specific T cells. Additionally, the potential...
3.
Dolla C, Padmapriyadarsini C, Thiruvengadam K, Lokhande R, Kinikar A, Paradkar M, et al.
Trans R Soc Trop Med Hyg
. 2019 Jun;
113(10):632-640.
PMID: 31225622
Background: Household contacts (HHCs) of TB patients are at high risk of developing evidence of latent TB infection (LTBI) and active disease from the index patient. We estimated the age-specific...
4.
Kumar N, Banurekha V, Nair D, Dolla C, Kumaran P, Babu S
Tuberculosis (Edinb)
. 2018 Mar;
108:127-135.
PMID: 29523313
Tuberculosis (TB) and diabetes mellitus (DM) remain vital disease burdens in developing countries and the dual burden of DM and TB clearly signifies a growing global public health concern. While...
5.
Anuradha R, Munisankar S, Bhootra Y, Dolla C, Kumaran P, Nutman T, et al.
Infect Immun
. 2017 Sep;
85(11).
PMID: 28874444
infection is associated with diminished antigen-specific Th1- and Th17-associated responses and enhanced Th2-associated responses. Interleukin-27 (IL-27) and IL-37 are two known anti-inflammatory cytokines that are highly expressed in infection. We...
6.
Kumar N, Moideen K, Dolla C, Kumaran P, Babu S
PLoS One
. 2017 May;
12(5):e0178000.
PMID: 28558065
Type 2 diabetes mellitus (DM) is associated with the down modulation of Th1, Th2 and Th17 responses in latent Mycobacterium tuberculosis infection but the role of prediabetes (PDM) in this...
7.
Anuradha R, Munisankar S, Bhootra Y, Dolla C, Kumaran P, Nutman T, et al.
PLoS Negl Trop Dis
. 2017 May;
11(5):e0005569.
PMID: 28459817
Background / Objectives: Helminth infections are known to influence T cell responses in latent tuberculosis (LTBI). Whether helminth infections also modulate B cell responses in helminth-tuberculosis co-infection is not known....
8.
Anuradha R, Munisankar S, Bhootra Y, Dolla C, Kumaran P, Nutman T, et al.
Infect Immun
. 2017 Feb;
85(4).
PMID: 28167672
Helminth infections are known to modulate cytokine responses in latent tuberculosis (LTB). However, very few studies have examined whether this modulation is reversible upon anthelmintic therapy. We measured the systemic...
9.
Anuradha R, Munisankar S, Bhootra Y, Dolla C, Kumaran P, Babu S
Tuberculosis (Edinb)
. 2016 Nov;
101:56-61.
PMID: 27865399
High body mass index (HBMI) has been shown to be protective against active tuberculosis (TB), although the biological mechanism underlying this protection is poorly understood. The immunological association between HBMI...
10.
Anuradha R, Munisankar S, Bhootra Y, Kumar N, Dolla C, Kumaran P, et al.
Clin Vaccine Immunol
. 2016 Feb;
23(4):339-45.
PMID: 26865593
Malnutrition, as defined by low body mass index (BMI), is a major risk factor for the development of active tuberculosis (TB), although the biological basis underlying this susceptibility remains poorly...