Paul J Niziolek
Overview
Explore the profile of Paul J Niziolek including associated specialties, affiliations and a list of published articles.
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14
Citations
1006
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Recent Articles
1.
Warmke L, Collier C, Niziolek P, Davis J, Zou Y, Michal M, et al.
Mod Pathol
. 2024 May;
37(7):100518.
PMID: 38763420
Appropriate classification of fusion-driven bone and soft tissue neoplasms continues to evolve, often relying on the careful integration of morphologic findings with immunohistochemical, molecular, and clinical data. Herein, we present...
2.
Newman C, Surowiec R, Swallow E, Metzger C, Kim J, Tomaschke A, et al.
Bone
. 2023 May;
173:116808.
PMID: 37207990
Chronic kidney disease (CKD) is characterized by secondary hyperparathyroidism and an increased risk of hip fractures predominantly related to cortical porosity. Unfortunately, bone mineral density measurements and high-resolution peripheral computed...
3.
Ladd L, Imel E, Niziolek P, Liu Z, Warden S, Liang Y, et al.
Skeletal Radiol
. 2020 Oct;
50(5):903-913.
PMID: 33009917
Objective: To characterize relationships between quantitative computed tomography bone mineral density measurements and other qualitative and quantitative imaging measures, as well as clinical metrics, in patients with autosomal dominant osteopetrosis...
4.
Cheema A, Niziolek P, Steinberg D, Kneeland B, Kazmers N, Bozentka D
J Hand Surg Am
. 2018 Jun;
43(12):1092-1097.
PMID: 29908930
Purpose: Reformatting computed tomography (CT) scans along the scaphoid longitudinal axis improves the ability to detect scaphoid fractures compared with reformats along the wrist axis. However, it remains unclear whether...
5.
Niziolek P, Bullock W, Warman M, Robling A
PLoS One
. 2015 Nov;
10(11):e0140775.
PMID: 26554834
The low density lipoprotein receptor-related protein-5 (LRP5), a co-receptor in the Wnt signaling pathway, modulates bone mass in humans and in mice. Lrp5 knock-out mice have severely impaired responsiveness to...
6.
Niziolek P, MacDonald B, Kedlaya R, Zhang M, Bellido T, He X, et al.
J Bone Miner Res
. 2015 Mar;
30(10):1822-30.
PMID: 25808845
Certain missense mutations affecting LRP5 cause high bone mass (HBM) in humans. Based on in vitro evidence, HBM LRP5 receptors are thought to exert their effects by providing resistance to...
7.
Cui Y, Niziolek P, MacDonald B, Alenina N, Matthes S, Jacobsen C, et al.
Nat Med
. 2014 Nov;
20(11):1229-30.
PMID: 25375917
No abstract available.
8.
Niziolek P, Warman M, Robling A
Bone
. 2012 Jul;
51(3):459-65.
PMID: 22750014
Mechanotransduction in bone requires components of the Wnt signaling pathway to produce structurally adapted bone elements. In particular, the Wnt co-receptor LDL-receptor-related protein 5 (LRP5) appears to be a crucial...
9.
Niziolek P, Farmer T, Cui Y, Turner C, Warman M, Robling A
Bone
. 2011 Aug;
49(5):1010-9.
PMID: 21855668
Mutations among genes that participate in the canonical Wnt signaling pathway can lead to drastically different skeletal phenotypes, ranging from severe osteoporosis to severe osteosclerosis. Many high-bone-mass (HBM) causing mutations...
10.
Cui Y, Niziolek P, MacDonald B, Zylstra C, Alenina N, Robinson D, et al.
Nat Med
. 2011 May;
17(6):684-91.
PMID: 21602802
The human skeleton is affected by mutations in low-density lipoprotein receptor-related protein 5 (LRP5). To understand how LRP5 influences bone properties, we generated mice with osteocyte-specific expression of inducible Lrp5...