Paul J Godowski
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Explore the profile of Paul J Godowski including associated specialties, affiliations and a list of published articles.
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12
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1227
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Recent Articles
1.
Xie M, Dai B, Hackney J, Sun T, Zhang J, Jackman J, et al.
Cell Rep Med
. 2023 Jul;
4(8):101130.
PMID: 37490914
Signal regulatory protein (SIRPα) is an immune inhibitory receptor expressed by myeloid cells to inhibit immune cell phagocytosis, migration, and activation. Despite the progress of SIRPα and CD47 antagonist antibodies...
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Levy O, Zarember K, Roy R, Cywes C, Godowski P, Wessels M
J Immunol
. 2004 Sep;
173(7):4627-34.
PMID: 15383597
Newborns are at increased risk of overwhelming infection, yet the mechanisms underlying this susceptibility are incompletely defined. In this study we report a striking 1- to 3-log decrease in sensitivity...
4.
Iwahashi M, Yamamura M, Aita T, Okamoto A, Ueno A, Ogawa N, et al.
Arthritis Rheum
. 2004 May;
50(5):1457-67.
PMID: 15146415
Objective: CD16 (IgG Fcgamma receptor type IIIA [FcgammaRIIIA])-expressing CD14+ monocytes express high levels of Toll-like receptor 2 (TLR-2) and are able to efficiently produce proinflammatory cytokines such as tumor necrosis...
5.
Schmidt K, Leung B, Kwong M, Zarember K, Satyal S, Navas T, et al.
J Immunol
. 2003 Dec;
172(1):138-43.
PMID: 14688319
Toll-like receptors (TLRs) play a fundamental role in the recognition of bacteria and viruses. TLR3 is activated by viral dsRNA and polyinosinic-polycytidylic acid (poly(I:C)), a synthetic mimetic of viral RNA....
6.
Hertz C, Wu Q, Porter E, Zhang Y, Weismuller K, Godowski P, et al.
J Immunol
. 2003 Dec;
171(12):6820-6.
PMID: 14662888
As pattern recognition receptors capable of eliciting responses to a diverse array of microbial products, Toll-like receptors (TLRs) participate in the activation of host defense mechanisms that protect against infectious...
7.
Levy O, Jean-Jacques R, Cywes C, Sisson R, Zarember K, Godowski P, et al.
Infect Immun
. 2003 Oct;
71(11):6344-53.
PMID: 14573654
Group B Streptococcus (GBS) is a major cause of newborn sepsis and meningitis and induces systemic release of tumor necrosis factor alpha (TNF-alpha), believed to play a role in morbidity...
8.
Krutzik S, Ochoa M, Sieling P, Uematsu S, Ng Y, Legaspi A, et al.
Nat Med
. 2003 Apr;
9(5):525-32.
PMID: 12692544
The expression and activation of Toll-like receptors (TLRs) was investigated in leprosy, a spectral disease in which clinical manifestations correlate with the type of immune response mounted toward Mycobacterium leprae....
9.
Ochoa M, Legaspi A, Hatziris Z, Godowski P, Modlin R, Sieling P
Immunology
. 2003 Jan;
108(1):10-5.
PMID: 12519297
To determine how distinct receptors of the immune system can contribute to innate immunity, we investigated the pattern of Toll-like receptor 1 (TLR1) and TLR2 expression in human lymphoid tissue....
10.
Sieling P, Chung W, Duong B, Godowski P, Modlin R
J Immunol
. 2002 Dec;
170(1):194-200.
PMID: 12496400
Bacterial lipopeptides (bLPs) are increasingly used as adjuvants to activate cell-mediated immune responses to foreign Ags. To explore mechanisms whereby bLPs adjuvant T cell responses, we stimulated human PBMCs with...