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Paul J Fadel

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Articles 177
Citations 3759
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Recent Articles
1.
Chang K, Haun T, Liu Z, Gil A, Taherzadeh Z, Fadel P, et al.
Alcohol Clin Exp Res (Hoboken) . 2025 Mar; PMID: 40059037
Background: The association between alcohol and hypertension has been predominantly based on office blood pressure (BP) measurements. However, little is known about the effect of alcohol use on nighttime BP...
2.
Autler A, Darling A, Skow R, Young B, Fadel P, Saunders E, et al.
Auton Neurosci . 2025 Mar; 259:103257. PMID: 40058187
Young women, who suffer from major depressive disorder (MDD) at twice the rate as young men, are particularly vulnerable to cardiovascular events triggered by emotional stress, an association that may...
3.
Washio T, Takeda R, Hissen S, Akins J, DSouza A, Wakeham D, et al.
Clin Auton Res . 2025 Feb; PMID: 40000578
Purpose: Recent studies have reported blunted increases in blood pressure (BP) during static handgrip (SHG) in patients with heart failure with preserved ejection fraction (HFpEF), which may be attributed to...
4.
Kissell C, Young B, Kaur J, Taherzadeh Z, Mohan P, Vianna L, et al.
Clin Auton Res . 2024 Nov; PMID: 39542982
Purpose: Patients with chronic kidney disease (CKD) are more than twice as likely to die from a cardiovascular event than those with normal kidney function. Although CKD may increase resting...
5.
Nandadeva D, Skow R, Martin Z, Patik J, Taherzadeh Z, Ortiz A, et al.
Am J Physiol Regul Integr Comp Physiol . 2024 Oct; 327(6):R580-R589. PMID: 39401485
The cerebral vasodilator response to increased arterial carbon dioxide (CO) concentration, termed cerebral vasomotor reactivity (CVMR), is used to assess cerebral vascular function. We sought to assess the within-day and...
6.
Plunkett M, Holwerda S, Young B, Fadel P, Fisher J
J Physiol . 2024 Jul; 602(16):3909-3927. PMID: 39073892
Type 2 diabetes (T2D) is often accompanied by hypertension, exaggerated blood pressure (BP) responses to sympatho-excitatory stressors, and raised cardiovascular disease risk. Appropriate respiratory-sympathetic coupling and sympathetic transduction to BP...
7.
Young B, Kissell C, Vranish J, Stephens B, Holwerda S, Fadel P
Am J Physiol Heart Circ Physiol . 2024 Jul; 327(3):H672-H680. PMID: 39058432
The prevalence of hypertension in non-Hispanic black (BL) individuals is the greatest of any racial/ethnic group. Whereas women generally display lower rates of hypertension than men of the same background,...
8.
Skow R, Sarma S, MacNamara J, Bartlett M, Wakeham D, Martin Z, et al.
Circ Heart Fail . 2024 Jul; 17(8):e011693. PMID: 39051098
Background: We identified peripherally limited patients using cardiopulmonary exercise testing and measured skeletal muscle oxygen transport and utilization during invasive single leg exercise testing to identify the mechanisms of the...
9.
Darling A, Young B, Skow R, Dominguez C, Saunders E, Fadel P, et al.
J Affect Disord . 2024 Jun; 361:322-332. PMID: 38897296
Background: Sympathetic and blood pressure (BP) hyper-reactivity to stress may contribute to increased cardiovascular disease (CVD) risk in adults with major depressive disorder (MDD); however, whether this is evident in...
10.
Takeda R, Hissen S, Akins J, Washio T, Hearon Jr C, MacNamara J, et al.
Hypertension . 2024 Feb; 81(4):917-926. PMID: 38385250
Background: We tested the hypothesis that patients with heart failure with preserved ejection fraction (HFpEF) would have greater muscle sympathetic nerve activity (MSNA) at rest and sympathetic reactivity during a...