Paul Havlak
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Explore the profile of Paul Havlak including associated specialties, affiliations and a list of published articles.
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18
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3118
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Recent Articles
1.
Chipman A, Ferrier D, Brena C, Qu J, Hughes D, Schroder R, et al.
PLoS Biol
. 2014 Nov;
12(11):e1002005.
PMID: 25423365
Myriapods (e.g., centipedes and millipedes) display a simple homonomous body plan relative to other arthropods. All members of the class are terrestrial, but they attained terrestriality independently of insects. Myriapoda...
2.
Maxwell E, Schnitzler C, Havlak P, Putnam N, Nguyen A, Moreland R, et al.
BMC Evol Biol
. 2014 Oct;
14:212.
PMID: 25281000
Background: The recent expansion of whole-genome sequence data available from diverse animal lineages provides an opportunity to investigate the evolutionary origins of specific classes of human disease genes. Previous studies...
3.
Nossa C, Havlak P, Yue J, Lv J, Vincent K, Brockmann H, et al.
Gigascience
. 2014 Jul;
3:9.
PMID: 24987520
Background: Horseshoe crabs are marine arthropods with a fossil record extending back approximately 450 million years. They exhibit remarkable morphological stability over their long evolutionary history, retaining a number of...
4.
Ryan J, Pang K, Schnitzler C, Nguyen A, Moreland R, Simmons D, et al.
Science
. 2013 Dec;
342(6164):1242592.
PMID: 24337300
An understanding of ctenophore biology is critical for reconstructing events that occurred early in animal evolution. Toward this goal, we have sequenced, assembled, and annotated the genome of the ctenophore...
5.
Simakov O, Marletaz F, Cho S, Edsinger-Gonzales E, Havlak P, Hellsten U, et al.
Nature
. 2012 Dec;
493(7433):526-31.
PMID: 23254933
Current genomic perspectives on animal diversity neglect two prominent phyla, the molluscs and annelids, that together account for nearly one-third of known marine species and are important both ecologically and...
6.
Saxer G, Havlak P, Fox S, Quance M, Gupta S, Fofanov Y, et al.
PLoS One
. 2012 Oct;
7(10):e46759.
PMID: 23056439
Spontaneous mutations play a central role in evolution. Despite their importance, mutation rates are some of the most elusive parameters to measure in evolutionary biology. The combination of mutation accumulation...
7.
Lv J, Havlak P, Putnam N
BMC Bioinformatics
. 2011 Dec;
12 Suppl 9:S11.
PMID: 22151646
Background: Many metazoan genomes conserve chromosome-scale gene linkage relationships ("macro-synteny") from the common ancestor of multicellular animal life 1234, but the biological explanation for this conservation is still unknown. Double...
8.
Liu Y, Qin X, Song X, Jiang H, Shen Y, Durbin K, et al.
BMC Genomics
. 2009 Apr;
10:180.
PMID: 19393050
Background: We present here the assembly of the bovine genome. The assembly method combines the BAC plus WGS local assembly used for the rat and sea urchin with the whole...
9.
Elsik C, Tellam R, Worley K, Gibbs R, Muzny D, Weinstock G, et al.
Science
. 2009 Apr;
324(5926):522-8.
PMID: 19390049
To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a core set...
10.
Roberts M, Zimin A, Hayes W, Hunt B, Ustun C, White J, et al.
PLoS One
. 2008 Mar;
3(3):e1836.
PMID: 18350171
The assembly methods used for whole-genome shotgun (WGS) data have a major impact on the quality of resulting draft genomes. We present a novel algorithm to generate a set of...