Paul G Smith
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Explore the profile of Paul G Smith including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
276
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Recent Articles
11.
Chaudhuri S, Smith P
Am J Respir Cell Mol Biol
. 2008 Apr;
39(3):270-8.
PMID: 18390476
Mechanical stress (cyclic deformational strain) increases proteins of cytoskeletal and contractile domains in airway smooth muscle (ASM) cells in a manner that increases cell contractility. Here we studied the role...
12.
Smith P, Dreshaj A, Chaudhuri S, Onder B, Mhanna M, Martin R
Am J Physiol Lung Cell Mol Physiol
. 2007 Jan;
292(1):L68-73.
PMID: 17215435
Exposure of rat pups to 100% oxygen is a model for studying neonatal lung injury. Airway reactivity is increased in this model, in part due to impaired airway smooth muscle...
13.
Cytoskeletal tension regulates both expression and degradation of h2-calponin in lung alveolar cells
Hossain M, Smith P, Wu K, Jin J
Biochemistry
. 2006 Dec;
45(51):15670-83.
PMID: 17176089
Calponin is an actin filament-associated regulatory protein, and its h2 isoform is expressed in lung alveolar epithelial cells under postnatal upregulation during lung development corresponding to the commencement of respiratory...
14.
Bai T, Bates J, Brusasco V, Camoretti-Mercado B, Chitano P, Deng L, et al.
J Appl Physiol (1985)
. 2004 Nov;
97(6):2029-34.
PMID: 15531570
The observation that the length-force relationship in airway smooth muscle can be shifted along the length axis by accommodating the muscle at different lengths has stimulated great interest. In light...
15.
Deng L, Fairbank N, Fabry B, Smith P, Maksym G
Am J Physiol Cell Physiol
. 2004 Apr;
287(2):C440-8.
PMID: 15070813
Mechanical stress (MS) causes cytoskeletal (CSK) and phenotypic changes in cells. Such changes in airway smooth muscle (ASM) cells might contribute to the pathophysiology of asthma. We have shown that...
16.
Smith P, Deng L, Fredberg J, Maksym G
Am J Physiol Lung Cell Mol Physiol
. 2003 Apr;
285(2):L456-63.
PMID: 12704020
We tested the hypothesis that cytoskeletal reorganization induced by cyclic strain increases cytoskeletal stiffness (G'). G' was measured by optical magnetic twisting cytometry in control cells and cells that had...
17.
Smith P, Roy C, Zhang Y, Chauduri S
Am J Respir Cell Mol Biol
. 2003 Mar;
28(4):436-42.
PMID: 12654632
Cultured airway smooth muscle cells subjected to cyclic strain respond with increased cytoskeletal organization and contractility resembling effects described with RhoA activation. To test the hypothesis that strain increases cell...
18.
Dearborn D, Smith P, Dahms B, Allan T, Sorenson W, Montana E, et al.
Pediatrics
. 2002 Sep;
110(3):627-37.
PMID: 12205270
Between 1993 and 2000, 30 infants were hospitalized with acute pulmonary hemorrhage at Rainbow Babies and Children's Hospital in Cleveland. Most infants presented with severe pulmonary symptoms requiring intensive support,...