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Paul Elbers

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Articles 46
Citations 389
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Recent Articles
11.
den Hengst F, Otten M, Elbers P, van Harmelen F, Francois-Lavet V, Hoogendoorn M
Artif Intell Med . 2024 Jan; 147:102742. PMID: 38184349
Reinforcement Learning (RL) has recently found many applications in the healthcare domain thanks to its natural fit to clinical decision-making and ability to learn optimal decisions from observational data. A...
12.
Thoral P, Elbers P
Intensive Care Med . 2023 Jun; 49(8):1027-1028. PMID: 37310484
No abstract available.
13.
Verhaeghe J, De Corte T, Sauer C, Hendriks T, Thijssens O, Ongenae F, et al.
Int J Med Inform . 2023 May; 175:105086. PMID: 37148868
Background: Atrial Fibrillation (AF) is the most common arrhythmia in the intensive care unit (ICU) and is associated with increased morbidity and mortality. Identification of patients at risk for AF...
14.
Michels E, van Amstel R, van Linge C, Schuurman A, Reijnders T, Sulzer T, et al.
Eur Respir J . 2023 Apr; 62(1). PMID: 37080568
Background: Coronavirus disease 2019 (COVID-19)-induced mortality occurs predominantly in older patients. Several immunomodulating therapies seem less beneficial in these patients. The biological substrate behind these observations is unknown. The aim...
15.
Bologheanu R, Kapral L, Laxar D, Maleczek M, Dibiasi C, Zeiner S, et al.
J Clin Med . 2023 Feb; 12(4). PMID: 36836046
Background: The optimal indication, dose, and timing of corticosteroids in sepsis is controversial. Here, we used reinforcement learning to derive the optimal steroid policy in septic patients based on data...
16.
Edinburgh T, Eglen S, Thoral P, Elbers P, Ercole A
GigaByte . 2023 Feb; 2022:gigabyte45. PMID: 36824503
Sepsis is a major healthcare problem with substantial mortality and a common reason for admission to the intensive care unit (ICU). For this reason, the management of sepsis is an...
17.
Yarnell C, Angriman F, Ferreyro B, Liu K, De Grooth H, Burry L, et al.
Crit Care . 2023 Feb; 27(1):67. PMID: 36814287
Background: The optimal thresholds for the initiation of invasive ventilation in patients with hypoxemic respiratory failure are unknown. Using the saturation-to-inspired oxygen ratio (SF), we compared lower versus higher hypoxemia...
18.
Lijovic L, Pelajic S, Hawchar F, Minev I, da Silva B, Angelucci A, et al.
J Crit Care . 2023 Feb; 75:154276. PMID: 36774818
Introduction: Accurate and actionable diagnosis of Acute Kidney Injury (AKI) ahead of time is important to prevent or mitigate renal insufficiency. The purpose of this study was to evaluate the...
19.
Huntjens D, Dijkstra J, Verwiel L, Slijkhuis M, Elbers P, Welkers M, et al.
Pharmaceutics . 2023 Jan; 15(1). PMID: 36678792
Herpes simplex virus (HSV) and cytomegalovirus (CMV) are DNA viruses that are common among humans. Severely immunocompromised patients are at increased risk of developing HSV or CMV disease due to...
20.
Sauer C, Chen L, Hyland S, Girbes A, Elbers P, Celi L
Lancet Digit Health . 2022 Sep; 4(12):e893-e898. PMID: 36154811
Analysis of electronic health records (EHRs) is an increasingly common approach for studying real-world patient data. Use of routinely collected data offers several advantages compared with other study designs, including...