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Paul Ciero

Explore the profile of Paul Ciero including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 314
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Recent Articles
1.
Tal A, Gunawardana-Zeigler S, Peng D, Tan Y, Munoz Perez N, Offenbacher R, et al.
Mol Cancer Ther . 2025 Jan; PMID: 39781890
Osteosarcoma (OS) is the most common primary malignant bone tumor in childhood. Patients who present with metastatic disease at diagnosis or relapse have a very poor prognosis, and this has...
2.
Tal A, Gunawardana-Zeigler S, Peng D, Tan Y, Munoz Perez N, Offenbacher R, et al.
bioRxiv . 2024 Dec; PMID: 39713389
Osteosarcoma (OS) is the most common primary malignant bone tumor in childhood. Patients who present with metastatic disease at diagnosis or relapse have a very poor prognosis, and this has...
3.
Offenbacher R, Jackson K, Hayashi M, Zhang J, Peng D, Tan Y, et al.
bioRxiv . 2024 Jul; PMID: 38948823
Polyamine metabolism and signaling play important roles in multiple cancers but have not previously been studied in Ewing sarcoma. Here, we show that blocking polyamine synthesis with D, L-alpha-difluoromethylornithine (DFMO)...
4.
Randolph M, Afifi M, Gorthi A, Weil R, Wilky B, Weinreb J, et al.
iScience . 2024 Feb; 27(2):108925. PMID: 38323009
We previously demonstrated that RNA helicase DDX3X (DDX3) can be a therapeutic target in Ewing sarcoma (EWS), but its role in EWS biology remains unclear. The present work demonstrates that...
5.
Randolph M, Afifi M, Gorthi A, Weil R, Wilky B, Weinreb J, et al.
bioRxiv . 2023 Jun; PMID: 37333164
We previously demonstrated that RNA helicase DDX3X (DDX3) can be a therapeutic target in Ewing sarcoma (EWS), but its role in EWS biology remains unclear. The present work demonstrates that...
6.
Maryanovich M, Zahalka A, Pierce H, Pinho S, Nakahara F, Asada N, et al.
Nat Med . 2019 Mar; 25(4):701. PMID: 30903101
In the version of this article originally published, the key for Fig. 4c was incorrect. The symbols for 'Sham' and 'Den' were reversed. The error has been corrected in the...
7.
Maryanovich M, Zahalka A, Pierce H, Pinho S, Nakahara F, Asada N, et al.
Nat Med . 2018 May; 24(6):782-791. PMID: 29736022
Aging of hematopoietic stem cells (HSCs) is associated with a decline in their regenerative capacity and multilineage differentiation potential, contributing to the development of blood disorders. The bone marrow microenvironment...
8.
Khan J, Mendelson A, Kunisaki Y, Birbrair A, Kou Y, Arnal-Estape A, et al.
Science . 2015 Dec; 351(6269):176-80. PMID: 26634440
Whereas the cellular basis of the hematopoietic stem cell (HSC) niche in the bone marrow has been characterized, the nature of the fetal liver niche is not yet elucidated. We...