Paul A Lapchak
Overview
Explore the profile of Paul A Lapchak including associated specialties, affiliations and a list of published articles.
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Articles
81
Citations
1447
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0
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Recent Articles
1.
Lapchak P, Boitano P, Bombien R, Chou D, Knight M, Muehle A, et al.
Neural Regen Res
. 2019 Aug;
14(12):2192-2198.
PMID: 31397359
Spinal cord ischemia associated with trauma and surgical procedures including thoraco-abdominal aortic aneurysm repair and thoracic endovascular aortic repair results in devastating clinical deficits in patients. Because spinal cord ischemia...
2.
Lapchak P, Boitano P, Bombien R, Cook D, Doyan S, Lara J, et al.
Exp Neurol
. 2018 Dec;
313:98-108.
PMID: 30521790
Ischemic stroke is an acute neurodegenerative disease that is extremely devastating to patients, their families and society. Stroke is inadequately treated even with endovascular procedures and reperfusion therapy. Using an...
3.
Lapchak P, Boitano P, de Couto G, Marban E
Exp Neurol
. 2018 Jun;
307:109-117.
PMID: 29908146
Acute ischemic stroke is devastating to patients and their families because of few viable therapeutic options to promote recovery after reperfusion windows close. Recent breakthroughs in biotechnology have resulted in...
4.
Lapchak P, Lara J, Boitano P
Transl Stroke Res
. 2017 Apr;
PMID: 28405804
Tissue plasminogen activator (tPA) is currently used in combination with endovascular procedures to enhance recanalization and cerebral reperfusion and is also currently administered as standard-of-care thrombolytic therapy to patients within...
5.
6.
Lapchak P, Zhang J
Transl Stroke Res
. 2017 Mar;
9(1):4-8.
PMID: 28283966
Important questions regarding the conduct of scientific research and data transparency have been raised in various scientific forums over the last 10 years. It is becoming clear, that in spite...
7.
8.
Lapchak P, Uteshev V
Transl Stroke Res
. 2017 Mar;
8(2):104-106.
PMID: 28251583
No abstract available.
9.
Lapchak P, Zhang J
Transl Stroke Res
. 2017 Jan;
8(4):307-317.
PMID: 28039575
Acute ischemic stroke is inadequately treated in the USA and worldwide due to a lengthy history of neuroprotective drug failures in clinical trials. The majority of victims must endure life-long...
10.
Lapchak P, Boitano P
Brain Res
. 2016 May;
1646:125-131.
PMID: 27180104
Tissue plasminogen activator (tPA) is the only FDA-approved treatment for stroke; tPA increases cerebral reperfusion, blood flow and improved behavior. Novel transcranial laser therapy (TLT) also enhances cerebral blood flow...