Patryk Skowron
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Explore the profile of Patryk Skowron including associated specialties, affiliations and a list of published articles.
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21
Citations
893
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Recent Articles
1.
Fan J, Erickson A, Carrillo-Garcia J, Wang X, Skowron P, Wang X, et al.
Dev Cell
. 2025 Jan;
PMID: 39862856
Distinguishing tumor maintenance genes from initiation, progression, and passenger genes is critical for developing effective therapies. We employed a functional genomic approach using the Lazy Piggy transposon to identify tumor...
2.
Jiang Z, Ju Y, Ali A, Chung P, Skowron P, Wang D, et al.
Nat Commun
. 2023 Jul;
14(1):4313.
PMID: 37463901
Metastatic breast-cancer is a major cause of death in women worldwide, yet the relationship between oncogenic drivers that promote metastatic versus primary cancer is still contentious. To elucidate this relationship...
3.
Hendrikse L, Haldipur P, Saulnier O, Millman J, Sjoboen A, Erickson A, et al.
Nature
. 2022 Nov;
612(7940):E12.
PMID: 36446943
No abstract available.
4.
Hendrikse L, Haldipur P, Saulnier O, Millman J, Sjoboen A, Erickson A, et al.
Nature
. 2022 Sep;
609(7929):1021-1028.
PMID: 36131014
Medulloblastoma (MB) comprises a group of heterogeneous paediatric embryonal neoplasms of the hindbrain with strong links to early development of the hindbrain. Mutations that activate Sonic hedgehog signalling lead to...
5.
Garancher A, Suzuki H, Haricharan S, Chau L, Masihi M, Rusert J, et al.
Nat Neurosci
. 2021 Dec;
25(1):127.
PMID: 34907396
No abstract available.
6.
Schachter N, Adams J, Skowron P, Kozma K, Lee C, Raghuram N, et al.
Nat Commun
. 2021 Sep;
12(1):5238.
PMID: 34475389
The most common events in breast cancer (BC) involve chromosome arm losses and gains. Here we describe identification of 1089 gene-centric common insertion sites (gCIS) from transposon-based screens in 8...
7.
Coltin H, Sundaresan L, Smith K, Skowron P, Massimi L, Eberhart C, et al.
Acta Neuropathol
. 2021 Aug;
142(5):859-871.
PMID: 34409497
Medulloblastoma, a common pediatric malignant central nervous system tumour, represent a small proportion of brain tumours in adults. Previously it has been shown that in adults, Sonic Hedgehog (SHH)-activated tumours...
8.
Skowron P, Farooq H, Cavalli F, Morrissy A, Ly M, Hendrikse L, et al.
Nat Commun
. 2021 Mar;
12(1):1749.
PMID: 33741928
Sonic hedgehog medulloblastoma encompasses a clinically and molecularly diverse group of cancers of the developing central nervous system. Here, we use unbiased sequencing of the transcriptome across a large cohort...
9.
Garancher A, Suzuki H, Haricharan S, Chau L, Masihi M, Rusert J, et al.
Nat Neurosci
. 2020 May;
23(7):842-853.
PMID: 32424282
Many immunotherapies act by enhancing the ability of cytotoxic T cells to kill tumor cells. Killing depends on T cell recognition of antigens presented by class I major histocompatibility complex...
10.
Suzuki H, Kumar S, Shuai S, Diaz-Navarro A, Gutierrez-Fernandez A, De Antonellis P, et al.
Nature
. 2019 Oct;
574(7780):707-711.
PMID: 31664194
In cancer, recurrent somatic single-nucleotide variants-which are rare in most paediatric cancers-are confined largely to protein-coding genes. Here we report highly recurrent hotspot mutations (r.3A>G) of U1 spliceosomal small nuclear...