Patrizia Polverino de Laureto
Overview
Explore the profile of Patrizia Polverino de Laureto including associated specialties, affiliations and a list of published articles.
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67
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1377
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Recent Articles
1.
Rizzotto E, Pierangelini A, Fongaro B, Leri M, Inciardi I, Trolese P, et al.
Int J Biol Macromol
. 2025 Jan;
294:139427.
PMID: 39756734
α-Synuclein (Syn) is an intrinsically disordered protein, abundant in presynaptic neurons. It is a constituent of the Lewis Body inclusions as amyloid fibrils, in Parkinson's disease patients. It populates an...
2.
Cesaro S, Orlando M, Bettin I, Longo C, Spagnoli G, Polverino de Laureto P, et al.
Protein Sci
. 2024 Dec;
34(1):e70024.
PMID: 39731543
Human succinic semialdehyde dehydrogenase is a mitochondrial enzyme fundamental in the neurotransmitter γ-aminobutyric acid catabolism. It catalyzes the NAD-dependent oxidative degradation of its derivative, succinic semialdehyde, to succinic acid. Mutations...
3.
Rizzotto E, Inciardi I, Fongaro B, Trolese P, Miolo G, Polverino de Laureto P
Eur J Pharm Biopharm
. 2024 Jul;
202:114421.
PMID: 39068036
No abstract available.
4.
Rizzotto E, Inciardi I, Fongaro B, Trolese P, Miolo G, Polverino de Laureto P
Eur J Pharm Biopharm
. 2024 Jun;
201:114387.
PMID: 38944210
Monoclonal antibodies (mAbs) are an essential class of therapeutic proteins for the treatment of cancer, autoimmune and rare diseases. During their production, storage, and administration processes, these proteins encounter various...
5.
Cappelletto E, Kwok S, Sorret L, Fuentes N, Medina A, Burleigh S, et al.
J Pharm Sci
. 2024 May;
113(8):2055-2064.
PMID: 38810881
This article evaluates the current gaps around the impact of post-manufacturing processes on the product qualities of protein-based biologics, with a focus on user centricity. It includes the evaluation of...
6.
Inciardi I, Rizzotto E, Gregoris F, Fongaro B, Sosic A, Minervini G, et al.
Biofactors
. 2024 May;
51(1):e2086.
PMID: 38801346
Parkinson's disease (PD) stands as a challenging neurodegenerative condition characterized by the emergence of Lewy Bodies (LBs), intracellular inclusions within dopaminergic neurons. These LBs harbor various proteins, prominently including α-Synuclein...
7.
De Diana E, Rizzotto E, Inciardi I, Menilli L, Coppola M, Polverino de Laureto P, et al.
Int J Pharm
. 2024 Feb;
654:123926.
PMID: 38401872
In the last years, monoclonal antibodies (mAbs) have rapidly escalated as biopharmaceuticals into cancer treatments, mainly for their target specificity accompanied by less side effects than the traditional chemotherapy, and...
8.
Fongaro B, Campara B, Yuri Moscatiello G, De Luigi A, Panzeri D, Sironi L, et al.
Int J Pharm
. 2023 Aug;
644:123319.
PMID: 37586576
The emergence of SARS-CoV-2 in Wuhan, China in 2019 has had a profound impact on humanity in every facet. While vaccines against this viral pathogen have been approved a year...
9.
Bisello G, Ribeiro R, Perduca M, Belviso B, Polverino de Laureto P, Giorgetti A, et al.
Protein Sci
. 2023 Jul;
32(8):e4732.
PMID: 37466248
Human aromatic amino acid decarboxylase (AADC) is a pyridoxal 5'-phosphate-dependent enzyme responsible for the biosynthesis of dopamine and serotonin, essential neurotransmitters involved in motor and cognitive abilities. Mutations in its...
10.
Vultaggio-Poma V, Scussel Bergamin L, Falzoni S, Tarantini M, Giuliani A, Sandona D, et al.
Purinergic Signal
. 2023 Apr;
20(1):83-89.
PMID: 37074620
ATP is a ubiquitous extracellular messenger released in a wide number of pathophysiological conditions. ATP is known to be present in minute amounts in the extracellular space in healthy tissues...