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Patrizia Larghero

Explore the profile of Patrizia Larghero including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 275
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Recent Articles
1.
Benz T, Larghero P, Meyer C, Muller M, Bruggmann D, Hentrich A, et al.
STAR Protoc . 2024 Dec; 6(1):103481. PMID: 39700011
KMT2A rearrangements are associated with a poor clinical outcome in infant, pediatric, and adult acute lymphoblastic and myeloid leukemia. Here, we present a protocol to reconstruct chromosomal translocations with different...
2.
Maurer-Granofszky M, Kohrer S, Fischer S, Schumich A, Nebral K, Larghero P, et al.
Haematologica . 2024 Jul; 109(7):2379-2381. PMID: 38946650
No abstract available.
3.
Burmeister T, Stroh A, Kehden B, Trautmann H, Meyer C, Marschalek R, et al.
Leukemia . 2024 Mar; 38(7):1600-1603. PMID: 38519799
No abstract available.
4.
Lopes B, Meyer C, Bouzada H, Kulp M, Maciel A, Larghero P, et al.
Leukemia . 2023 Jun; 37(8):1727-1731. PMID: 37386080
No abstract available.
5.
Maurer-Granofszky M, Kohrer S, Fischer S, Schumich A, Nebral K, Larghero P, et al.
Haematologica . 2023 Jun; 109(3):740-750. PMID: 37345487
Pediatric acute myeloid leukemia (AML) is a highly heterogeneous disease making standardized measurable residual disease (MRD) assessment challenging. Currently, patient-specific DNA-based assays are only rarely applied for MRD assessment in...
6.
Kulp M, Larghero P, Alten J, Cario G, Eckert C, Caye-Eude A, et al.
Leukemia . 2023 Apr; 37(6):1216-1233. PMID: 37100882
KMT2A-rearranged acute lymphoblastic infant leukemia (KMT2A-r iALL) is associated with outsize risk of relapse and relapse mortality. We previously reported strong upregulation of the immediate early gene EGR3 in KMT2A::AFF1...
7.
Kulp M, Siemund A, Larghero P, Dietz A, Alten J, Cario G, et al.
iScience . 2022 Jul; 25(7):104613. PMID: 35800767
The most frequent genetic aberration leading to infant ALL (iALL) is the chromosomal translocation t(4;11), generating the fusion oncogenes : and :, respectively. -r iALL displays a dismal prognosis through...
8.
Kowarz E, Krutzke L, Kulp M, Streb P, Larghero P, Reis J, et al.
Elife . 2022 Jan; 11. PMID: 35084333
To fight the COVID-19 pandemic caused by the RNA virus SARS-CoV-2, a global vaccination campaign is in progress to achieve the immunization of billions of people mainly with adenoviral vector-...
9.
de Matos R, Ferreira G, Meyer C, Marschalek R, Larghero P, Ribeiro R, et al.
J Pediatr Hematol Oncol . 2021 Dec; 44(3):e719-e722. PMID: 34966090
About 25% of the patients with the translocation t(11;19)(q23;p13.3)/KMT2A-MLLT1 present three-way or more complex fusions, associated with a worse prognosis, suggesting that a particular mechanism creates functional KMT2A fusions for...
10.
Bataller A, Guijarro F, Caye-Eude A, Strullu M, Sterin A, Molina O, et al.
Blood Adv . 2021 Oct; 5(24):5617-5620. PMID: 34638131
No abstract available.