Patrik Danielson
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Explore the profile of Patrik Danielson including associated specialties, affiliations and a list of published articles.
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51
Citations
999
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Recent Articles
1.
Zhang Q, Zhou X, Zhang W, Wang X, Dou S, Zhao L, et al.
FASEB J
. 2024 Dec;
38(23):e70236.
PMID: 39652089
Keratocytes are the primary resident cells in the corneal stroma. They play an essential role in maintaining corneal physiological function. Studying the factors that affect the phenotype and behavior of...
2.
Zhou X, Li J, Backman L, Danielson P
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36232373
Interleukin-1 (IL-1) and transforming growth factor-beta (TGFβ) are important cytokines involved in corneal wound healing. Here, we studied the effect of these cytokines on corneal stromal cell (keratocyte) differentiation. IL-1β...
3.
Prittinen J, Zhou X, Bano F, Backman L, Danielson P
Connect Tissue Res
. 2021 Dec;
63(5):443-452.
PMID: 34894951
Purpose/aim: Corneal injury is a major cause of impaired vision around the globe. The fine structure of the corneal stroma plays a pivotal role in the phenotype and behavior of...
4.
Zhou X, Backman L, Danielson P
Sci Rep
. 2021 Apr;
11(1):7360.
PMID: 33795727
Scar formation as a result of corneal wound healing is a leading cause of blindness. It is a challenge to understand why scar formation is more likely to occur in...
5.
Chen J, Backman L, Zhang W, Ling C, Danielson P
ACS Biomater Sci Eng
. 2021 Jan;
6(9):5162-5171.
PMID: 33455266
Corneal tissue engineering is an alternative way to solve the problem of lack of corneal donor tissue in corneal transplantation. Keratocytes with a normal phenotype and function in tissue-engineered cornea...
6.
Zhang W, Chen J, Qu M, Backman L, Zhang A, Liu H, et al.
Adv Healthc Mater
. 2020 Aug;
9(17):e2000591.
PMID: 32743953
Corneal injury due to ocular trauma or infection is one of the most challenging vision impairing pathologies that exists. Many studies focus on the pro-inflammatory and pro-angiogenic effects of interleukin-1β...
7.
Sloniecka M, Danielson P
J Cell Mol Med
. 2020 Mar;
24(8):4850-4862.
PMID: 32176460
Acetylcholine (ACh) has been reported to play various physiological roles, including wound healing in the cornea. Here, we study the role of ACh in the transition of corneal fibroblasts into...
8.
Wang X, Qu M, Li J, Danielson P, Yang L, Zhou Q
Invest Ophthalmol Vis Sci
. 2019 Aug;
60(10):3669-3679.
PMID: 31469894
Purpose: To investigate the presence and role of fibroblast senescence in the dynamic process of corneal wound healing involving stromal cell apoptosis, proliferation, and differentiation. Methods: An in vivo corneal...
9.
Sloniecka M, Danielson P
J Mol Med (Berl)
. 2019 Aug;
97(10):1477-1489.
PMID: 31399750
Fibrosis is characterized by hardening, overgrowth, and development of scars in various tissues as a result of faulty reparative processes, diseases, or chronic inflammation. During the fibrotic process in the...
10.
Chen J, Zhang W, Backman L, Kelk P, Danielson P
Br J Ophthalmol
. 2018 Jan;
102(4):562-569.
PMID: 29306866
Aims: To explore the role of corneal-shaped static mechanical strain on the differentiation of human periodontal ligament stem cells (PDLSCs) into keratocytes and the possible synergistic effects of mechanics and...