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Patrick Munzer

Explore the profile of Patrick Munzer including associated specialties, affiliations and a list of published articles. Areas
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Articles 55
Citations 1094
Followers 0
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Recent Articles
1.
de Jonckheere B, Kollotzek F, Munzer P, Gob V, Fischer M, Mott K, et al.
Nat Cardiovasc Res . 2024 Aug; 2(12):1327. PMID: 39196157
No abstract available.
2.
Seizer P, von Ungern-Sternberg S, Haug V, Dicenta V, Rosa A, Butt E, et al.
Cardiovasc Res . 2024 Jan; 120(4):385-402. PMID: 38175781
Aims: Cyclophilin A (CyPA) induces leucocyte recruitment and platelet activation upon release into the extracellular space. Extracellular CyPA therefore plays a critical role in immuno-inflammatory responses in tissue injury and...
3.
Rohlfing A, Kremser M, Schaale D, Dicenta-Baunach V, Laspa Z, Fu X, et al.
Thromb Res . 2024 Jan; 234:63-74. PMID: 38171216
Background And Aims: Hemolysis is a known risk factor for thrombosis resulting in critical limb ischemia and microcirculatory disturbance and organ failure. Intravasal hemolysis may lead to life-threatening complications due...
4.
de Jonckheere B, Kollotzek F, Munzer P, Gob V, Fischer M, Mott K, et al.
Nat Cardiovasc Res . 2023 Dec; 2:835-852. PMID: 38075556
During megakaryopoiesis, megakaryocytes (MK) undergo cellular morphological changes with strong modification of membrane composition and lipid signaling. Here we adopt a lipid-centric multiomics approach to create a quantitative map of...
5.
Zdanyte M, Borst O, Munzer P
Front Cardiovasc Med . 2023 Jun; 10:1155512. PMID: 37283578
Formation of Neutrophil Extracellular Traps (NETosis), accompanied by the release of extracellular decondensed chromatin and pro-inflammatory as well as pro-thrombotic factors, is a pivotal element in the development and progression...
6.
Manke M, Roslan A, Walker B, Munzer P, Kollotzek F, Peng B, et al.
J Thromb Haemost . 2023 Apr; 21(7):1957-1966. PMID: 37054918
Background: Pathophysiologic platelet activation leads to thrombo-occlusive diseases such as myocardial infarction or ischemic stroke. Niemann-Pick C1 protein (NPC1) is involved in the regulation of lysosomal lipid trafficking and calcium...
7.
Fink A, Rohlfing A, Dicenta V, Schaale D, Kremser M, Laspa Z, et al.
Thromb Haemost . 2023 Apr; 123(7):679-691. PMID: 37037200
Introduction:  Hemolysis results in release of free hemoglobin and hemin liberation from erythrocytes. Hemin has been described to induce platelet activation and to trigger thrombosis. Methods:  We evaluated the effect...
8.
Schutte J, Manke M, Hemmen K, Munzer P, Schorg B, Ramos G, et al.
Circ Res . 2023 Mar; 132(7):e96-e113. PMID: 36891903
Background: Platelets can infiltrate ischemic myocardium and are increasingly recognized as critical regulators of inflammatory processes during myocardial ischemia and reperfusion (I/R). Platelets contain a broad repertoire of microRNAs (miRNAs),...
9.
Rohlfing A, Kolb K, Sigle M, Ziegler M, Bild A, Munzer P, et al.
Nat Commun . 2022 Apr; 13(1):1823. PMID: 35383158
Platelet activation plays a critical role in thrombosis. Inhibition of platelet activation is a cornerstone in treatment of acute organ ischemia. Platelet ACKR3 surface expression is independently associated with all-cause...
10.
Munzer P, Borst O
Cells . 2022 Feb; 11(4). PMID: 35203269
Thrombo-occlusive diseases such as myocardial infarction, ischemic stroke and deep vein thrombosis with subsequent pulmonary embolism still represent a major health burden worldwide. Besides the cells of the vasculature or...