Patrick Marcellin
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Explore the profile of Patrick Marcellin including associated specialties, affiliations and a list of published articles.
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312
Citations
16355
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Recent Articles
1.
Buti M, Lim Y, Chan H, Agarwal K, Marcellin P, Brunetto M, et al.
Aliment Pharmacol Ther
. 2024 Sep;
60(11-12):1573-1586.
PMID: 39327857
Background: In two phase 3 studies, tenofovir alafenamide (TAF) showed non-inferior efficacy versus tenofovir disoproxil fumarate (TDF), with more favourable renal and bone safety in patients with chronic hepatitis B...
2.
Xu Z, Gnouamozi G, Rueger S, Shea P, Buti M, Chan H, et al.
Am J Hum Genet
. 2024 May;
111(6):1018-1034.
PMID: 38749427
Evolutionary changes in the hepatitis B virus (HBV) genome could reflect its adaptation to host-induced selective pressure. Leveraging paired human exome and ultra-deep HBV genome-sequencing data from 567 affected individuals...
3.
Chan H, Buti M, Lim Y, Agarwal K, Marcellin P, Brunetto M, et al.
Am J Gastroenterol
. 2023 Aug;
119(3):486-496.
PMID: 37561058
Introduction: The results from 2 phase 3 studies, through 2 years, in chronic hepatitis B infection showed tenofovir alafenamide (TAF) had similar efficacy to tenofovir disoproxil fumarate (TDF) with superior...
4.
Aggarwal A, Odorizzi P, Brodbeck J, van Buuren N, Moon C, Chang S, et al.
JHEP Rep
. 2023 Mar;
5(4):100664.
PMID: 36908748
Background & Aims: Patterns of liver HBV antigen expression have been described but not quantified at single-cell resolution. We applied quantitative techniques to liver biopsies from individuals with chronic hepatitis...
5.
Wagner J, Yuen L, Littlejohn M, Sozzi V, Jackson K, Martin R, et al.
Aliment Pharmacol Ther
. 2022 Nov;
57(5):509-523.
PMID: 36427857
Backgrounds And Aims: We investigated associations between hepatitis B virus (HBV) genome-length haplotype number (HN) at baseline in subjects with HBeAg-positive chronic hepatitis B (CHB), and the likelihood of achieving...
6.
Cardoso A, Figueiredo-Mendes C, Villela-Nogueira C, Marcellin P
Viruses
. 2022 Apr;
14(4).
PMID: 35458391
Staging fibrosis accurately has always been a challenge in viral hepatitis and other liver diseases. Liver biopsy is an imperfect gold standard due to its intra and interobserver agreement limitations...
7.
van Buuren N, Ramirez R, Soulette C, Suri V, Han D, May L, et al.
JHEP Rep
. 2022 Mar;
4(4):100449.
PMID: 35295767
Background & Aims: HBV infects over 257 million people worldwide and is associated with the development of hepatocellular carcinoma (HCC). Integration of HBV DNA into the host genome is likely...
8.
Ollivier-Hourmand I, Repesse Y, Nahon P, Chaffaut C, Dao T, Nguyen T, et al.
Liver Int
. 2022 Jan;
42(6):1386-1400.
PMID: 35025128
Background And Aims: Non-O blood group promotes deep vein thrombosis and liver fibrosis in both general population and hepatitis C. We aimed to evaluate the influence of Non-O group on...
9.
van Buuren N, Ramirez R, Turner S, Chen D, Suri V, Aggarwal A, et al.
JHEP Rep
. 2021 Dec;
4(1):100388.
PMID: 34950863
Background & Aims: We aim to describe the liver immune microenvironment by analyzing liver biopsies from patients with chronic HBV infection (CHB). Host immune cell signatures and their corresponding localization...
10.
Loureiro D, Castelnau C, Tout I, Boyer N, Narguet S, Menasria Benazzouz S, et al.
Liver Int
. 2021 Jun;
41 Suppl 1:30-37.
PMID: 34155804
Hepatitis delta virus (HDV) infection is a defective virus requiring hepatitis B virus (HBV) for its complete replication cycle. HDV is a small hepatotropic RNA virus and around 15 to...