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Patrick M Vanderboom

Explore the profile of Patrick M Vanderboom including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 498
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Recent Articles
11.
Vanderboom P, Dasari S, Ruegsegger G, Pataky M, Lucien F, Heppelmann C, et al.
Cell Rep Methods . 2021 Aug; 1(3). PMID: 34355211
Extracellular vesicles (EVs) are released into blood from multiple organs and carry molecular cargo that facilitates inter-organ communication and an integrated response to physiological and pathological stimuli. Interrogation of the...
12.
Mun D, Vanderboom P, Madugundu A, Garapati K, Chavan S, Peterson J, et al.
J Proteome Res . 2021 Jul; 20(8):4165-4175. PMID: 34292740
Since the recent outbreak of COVID-19, there have been intense efforts to understand viral pathogenesis and host immune response to combat SARS-CoV-2. It has become evident that different host alterations...
13.
Karon B, Donato L, Bridgeman A, Blommel J, Kipp B, Maus A, et al.
Clin Chem . 2021 Jul; 67(11):1545-1553. PMID: 34240163
Background: We evaluated the analytical sensitivity and specificity of 4 rapid antigen diagnostic tests (Ag RDTs) for severe acute respiratory syndrome coronavirus 2, using reverse transcription quantitative PCR (RT-qPCR) as...
14.
Renuse S, Vanderboom P, Maus A, Kemp J, Gurtner K, Madugundu A, et al.
EBioMedicine . 2021 Jul; 69:103465. PMID: 34229274
Background: The COVID-19 pandemic caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) has overwhelmed health systems worldwide and highlighted limitations of diagnostic testing. Several types of diagnostic tests including RT-PCR-based...
15.
Chavan S, Mangalaparthi K, Singh S, Renuse S, Vanderboom P, Madugundu A, et al.
J Proteome Res . 2021 Jun; 20(7):3404-3413. PMID: 34077217
SARS-CoV-2 infection has become a major public health burden and affects many organs including lungs, kidneys, the liver, and the brain. Although the virus is readily detected and diagnosed using...
16.
Ruegsegger G, Vanderboom P, Dasari S, Klaus K, Kabiraj P, McCarthy C, et al.
JCI Insight . 2019 Sep; 4(18). PMID: 31534057
Insulin resistance associates with increased risk for cognitive decline and dementia; however, the underpinning mechanisms for this increased risk remain to be fully defined. As insulin resistance impairs mitochondrial oxidative...
17.
Nasr S, Dasari S, Lieske J, Benson L, Vanderboom P, Holtz-Heppelmann C, et al.
Kidney Int . 2019 Apr; 95(5):1269-1272. PMID: 31010480
Fibrillary glomerulonephritis (FGN) is a rare glomerular disease. Kidney biopsy is required to establish the diagnosis. Recent studies have identified abundant glomerular deposition of DNAJB9 as a unique histological marker...
18.
Ruegsegger G, Manjunatha S, Summer P, Gopala S, Zabeilski P, Dasari S, et al.
FASEB J . 2019 Jan; 33(3):4458-4472. PMID: 30676773
Despite the strong association between diabetes and dementia, it remains to be fully elucidated how insulin deficiency adversely affects brain functions. We show that insulin deficiency in streptozotocin-induced diabetic mice...
19.
Mills J, Kohlhagen M, Dasari S, Vanderboom P, Kyle R, Katzmann J, et al.
Clin Chem . 2016 Aug; 62(10):1334-44. PMID: 27540026
Background: Electrophoretic separation of serum and urine proteins has played a central role in diagnosing and monitoring plasma cell disorders. Despite limitations in resolution and analytical sensitivity, plus the necessity...
20.
Kohlhagen M, Barnidge D, Mills J, Stoner J, Gurtner K, Liptac A, et al.
Clin Chem . 2016 Aug; 62(10):1345-52. PMID: 27515443
Background: Current recommendations for screening for monoclonal gammopathies include serum protein electrophoresis (PEL), imunofixation electrophoresis (IFE), and free light chain (FLC) ratios to identify or rule out an M-protein. The...