Patrick Lypaczewski
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Explore the profile of Patrick Lypaczewski including associated specialties, affiliations and a list of published articles.
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Citations
246
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Recent Articles
1.
Boussoffara T, Labidi I, Trimeche M, Chelbi I, Dachraoui K, Msallem N, et al.
NPJ Vaccines
. 2025 Feb;
10(1):31.
PMID: 39952958
Dogs are the main reservoir host of Leishmania infantum, etiological agent of zoonotic visceral leishmaniasis (ZVL). An effective vaccine against Canine Visceral Leishmaniasis (CVL) will help the control and elimination...
2.
Qin C, Lypaczewski P, Sayeed A, Cuenod A, Brinkley L, Creasy-Marrazzo A, et al.
bioRxiv
. 2024 Nov;
PMID: 39605465
Cholera is a diarrhoeal disease caused by . It remains a major public health challenge in the endemic region around the Bay of Bengal. Over decadal time scales, one lineage...
3.
Jain M, Sangma D, Parida L, Negi R, Negi A, Matlashewski G, et al.
Front Cell Infect Microbiol
. 2024 Nov;
14:1454002.
PMID: 39559700
Visceral leishmaniasis (VL) caused by in South-East Asian endemic countries including India, Nepal and Bangladesh has been the primary focus of the ongoing VL elimination program. With a major reduction...
4.
Lypaczewski P, Chauhan Y, Paulini K, Thakur L, Chauhan S, Roy E, et al.
Emerg Infect Dis
. 2024 Aug;
30(9):1957-1959.
PMID: 39174021
The clinical manifestation of leishmaniasis has historically been determined by the Leishmania species involved. However, recent emergence of novel Leishmania lineages has caused atypical pathologies. We isolated and characterized 2...
5.
Lypaczewski P, Chac D, Dunmire C, Tandoc K, Chowdhury F, Khan A, et al.
Microbiol Spectr
. 2024 Jun;
12(8):e0078524.
PMID: 38916318
Importance: O1, the bacterium that causes cholera, is ingested in contaminated food or water and then colonizes the upper small intestine and is excreted in stool. Shed genomes from stool...
6.
Lypaczewski P, Chac D, Dunmire C, Tandoc K, Chowdhury F, Khan A, et al.
bioRxiv
. 2024 Feb;
PMID: 38370713
O1 causes the diarrheal disease cholera, and the small intestine is the site of active infection. During cholera, cholera toxin is secreted from and induces a massive fluid influx into...
7.
Dey R, Alshaweesh J, Singh K, Lypaczewski P, Karmakar S, Klenow L, et al.
Nat Commun
. 2023 Nov;
14(1):7028.
PMID: 37919280
The leishmanin skin test was used for almost a century to detect exposure and immunity to Leishmania, the causative agent of leishmaniasis, a major neglected tropical disease. Due to a...
8.
Karmakar S, Volpedo G, Zhang W, Lypaczewski P, Ismail N, Oliveira F, et al.
NPJ Vaccines
. 2022 Dec;
7(1):157.
PMID: 36463228
Leishmaniasis is one of the top neglected tropical diseases with significant morbidity and mortality in low and middle-income countries (LMIC). However, this disease is also spreading in the developed world....
9.
Paulini K, Lypaczewski P, Zhang W, Perera D, Ndao M, Matlashewski G
Trop Med Infect Dis
. 2022 Nov;
7(11).
PMID: 36422936
The protozoan parasite is a causative agent of the neglected tropical disease known as visceral leishmaniasis, which can be lethal when untreated. Studying viru-lence factors is crucial in determining how...
10.
Lypaczewski P, Matlashewski G
Lancet Microbe
. 2022 May;
2(6):e250-e258.
PMID: 35544170
Background: Leishmaniasis is a neglected tropical disease transmitted by infected sandflies that results in diverse human pathologies contingent on the species of Leishmania. Leishmania donovani causes highly virulent fatal visceral...