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Patrick Evans

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Articles 20
Citations 709
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Recent Articles
1.
Nakazawa M, Harada G, Ghanem P, Bubie A, Kiedrowski L, Murray J, et al.
Cancer Res Commun . 2024 Feb; 4(3):786-795. PMID: 38407352
Significance: In a large-scale, contemporary cohort of patients with advanced ALK-positive NSCLC, we evaluated molecular characteristics and their impact on acquired resistance mutations and clinical outcomes. Our findings that certain...
2.
Evans P, Nagai T, Konkashbaev A, Zhou D, Knapik E, Gamazon E
Curr Protoc . 2024 Feb; 4(2):e981. PMID: 38314955
Transcriptome-wide association study (TWAS) methodologies aim to identify genetic effects on phenotypes through the mediation of gene transcription. In TWAS, in silico models of gene expression are trained as functions...
3.
Hirbo J, Pasutto F, Gamazon E, Evans P, Pawar P, Berner D, et al.
BMC Genomics . 2023 Feb; 24(1):75. PMID: 36797672
Background: Exfoliation syndrome (XFS) is an age-related systemic disorder characterized by excessive production and progressive accumulation of abnormal extracellular material, with pathognomonic ocular manifestations. It is the most common cause...
4.
Buzard B, Evans P, Schroeder T
Kans J Med . 2021 Mar; 14:73-76. PMID: 33763182
Introduction: Blood cultures are the gold standard for identifying bloodstream infections. The Clinical and Laboratory Standards Institute recommends a blood culture contamination rate of less than 3%. Contamination can lead...
5.
Oliva M, Munoz-Aguirre M, Kim-Hellmuth S, Wucher V, Gewirtz A, Cotter D, et al.
Science . 2020 Sep; 369(6509). PMID: 32913072
Many complex human phenotypes exhibit sex-differentiated characteristics. However, the molecular mechanisms underlying these differences remain largely unknown. We generated a catalog of sex differences in gene expression and in the...
6.
Evans P, Cox N, Gamazon E
PeerJ . 2020 Aug; 8:e9554. PMID: 32765967
The development of explanatory models of protein sequence evolution has broad implications for our understanding of cellular biology, population history, and disease etiology. Here we analyze the GTEx transcriptome resource...
7.
Damodara Kannan A, Evans P, Parameswaran P
Bioresour Technol . 2020 May; 310:123425. PMID: 32361646
This study evaluates the microbial community development in the suspended sludge within a pilot-scale gas sparged Anaerobic membrane bioreactor (AnMBR) under ambient conditions, as well as understand the influence of...
8.
Zhong X, Yin Z, Jia G, Zhou D, Wei Q, Faucon A, et al.
Genet Med . 2020 Apr; 22(7):1191-1200. PMID: 32296164
Purpose: The increasing use of electronic health records (EHRs) and biobanks offers unique opportunities to study Mendelian diseases. We described a novel approach to summarize clinical manifestations from patient EHRs...
9.
Lwin A, Zeng J, Evans P, Phung M, Hynes K, Price E, et al.
Urology . 2020 Jan; 138:119-124. PMID: 31962119
Objective: To assess the safety, feasibility and treatment outcomes of holmium laser enucleation of the prostate (HoLEP) as a same day surgery (SDS). Methods: HoLEPs performed from November 2013 to...
10.
Colbran L, Gamazon E, Zhou D, Evans P, Cox N, Capra J
Nat Ecol Evol . 2019 Oct; 3(11):1598-1606. PMID: 31591491
Sequencing DNA derived from archaic bones has enabled genetic comparison of Neanderthals and anatomically modern humans (AMHs), and revealed that they interbred. However, interpreting what genetic differences imply about their...