Patrick D Evans
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Explore the profile of Patrick D Evans including associated specialties, affiliations and a list of published articles.
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9
Citations
708
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Recent Articles
1.
Mekel-Bobrov N, Posthuma D, Gilbert S, Lind P, Gosso M, Luciano M, et al.
Hum Mol Genet
. 2007 Jan;
16(6):600-8.
PMID: 17220170
Recent studies have made great strides towards identifying putative genetic events underlying the evolution of the human brain and its emergent cognitive capacities. One of the most intriguing findings is...
2.
Evans P, Mekel-Bobrov N, Vallender E, Hudson R, Lahn B
Proc Natl Acad Sci U S A
. 2006 Nov;
103(48):18178-83.
PMID: 17090677
At the center of the debate on the emergence of modern humans and their spread throughout the globe is the question of whether archaic Homo lineages contributed to the modern...
3.
Evans P, Vallender E, Lahn B
Gene
. 2006 Apr;
375:75-9.
PMID: 16631324
Primary microcephaly is a developmental defect of the brain characterized by severely reduced brain size but an absence of other overt abnormalities. Mutations in several loci have been linked to...
4.
Mekel-Bobrov N, Gilbert S, Evans P, Vallender E, Anderson J, Hudson R, et al.
Science
. 2005 Sep;
309(5741):1720-2.
PMID: 16151010
The gene ASPM (abnormal spindle-like microcephaly associated) is a specific regulator of brain size, and its evolution in the lineage leading to Homo sapiens was driven by strong positive selection....
5.
Evans P, Gilbert S, Mekel-Bobrov N, Vallender E, Anderson J, Vaez-Azizi L, et al.
Science
. 2005 Sep;
309(5741):1717-20.
PMID: 16151009
The gene Microcephalin (MCPH1) regulates brain size and has evolved under strong positive selection in the human evolutionary lineage. We show that one genetic variant of Microcephalin in modern humans,...
6.
Dorus S, Vallender E, Evans P, Anderson J, Gilbert S, Mahowald M, et al.
Cell
. 2004 Dec;
119(7):1027-40.
PMID: 15620360
Human evolution is characterized by a dramatic increase in brain size and complexity. To probe its genetic basis, we examined the evolution of genes involved in diverse aspects of nervous...
7.
Dorus S, Evans P, Wyckoff G, Choi S, Lahn B
Nat Genet
. 2004 Nov;
36(12):1326-9.
PMID: 15531881
Postcopulatory sperm competition is a key aspect of sexual selection and is believed to drive the rapid evolution of both reproductive physiology and reproduction-related genes. It is well-established that mating...
8.
Evans P, Anderson J, Vallender E, Choi S, Lahn B
Hum Mol Genet
. 2004 Apr;
13(11):1139-45.
PMID: 15056607
The defining process in the evolution of primates and particularly humans is the dramatic expansion of the brain. While many types of genes could potentially contribute to this process, genes...
9.
Evans P, Anderson J, Vallender E, Gilbert S, Malcom C, Dorus S, et al.
Hum Mol Genet
. 2004 Jan;
13(5):489-94.
PMID: 14722158
A prominent trend in the evolution of humans is the progressive enlargement of the cerebral cortex. The ASPM (Abnormal spindle-like microcephaly associated) gene has the potential to play a role...