Patrick Bastien
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Explore the profile of Patrick Bastien including associated specialties, affiliations and a list of published articles.
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77
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1561
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Recent Articles
1.
Pasquier G, Demar M, Lami P, Zribi A, Marty P, Buffet P, et al.
PLoS Negl Trop Dis
. 2022 Oct;
16(10):e0010745.
PMID: 36206322
Background: In France, leishmaniasis is endemic in the Mediterranean region, in French Guiana and to a lesser extent, in the French West Indies. This study wanted to provide an updated...
2.
Brenier-Pinchart M, Filisetti D, Cassaing S, Varlet-Marie E, Robert-Gangneux F, Delhaes L, et al.
J Mol Diagn
. 2022 Apr;
24(6):687-696.
PMID: 35452843
Real-time PCR plays a crucial role in the diagnosis of toxoplasmosis. In this multicenter study, the Toxoplasma RealCycler Universal assay was assessed for the diagnosis of toxoplasmosis by eight reference...
3.
Singh P, Samanta K, Kebe N, Michel G, Legrand B, Sitnikova V, et al.
Bioorg Chem
. 2021 Dec;
119:105539.
PMID: 34894575
It is urgent to develop less toxic and more efficient treatments for leishmaniases and trypanosomiases. We explore the possibility to target the parasite mitochondrial HslVU protease, which is essential for...
4.
Pereira A, Parreira R, Cristovao J, Vitale F, Bastien P, Campino L, et al.
Vet Parasitol
. 2021 Jul;
298:109531.
PMID: 34293586
Zoonotic visceral leishmaniosis is a worldwide severe disease caused by Leishmania infantum, a protozoan that has phlebotomine sand flies as vectors and dogs as primary reservoir hosts. Over the last...
5.
Corrales R, Vaselek S, Neish R, Berry L, Brunet C, Crobu L, et al.
PLoS Pathog
. 2021 Jun;
17(6):e1009666.
PMID: 34143858
Leishmania parasites possess a unique and complex cytoskeletal structure termed flagellum attachment zone (FAZ) connecting the base of the flagellum to one side of the flagellar pocket (FP), an invagination...
6.
Brenier-Pinchart M, Robert-Gangneux F, Accoceberry I, Pichard S, Garnaud C, Fricker-Hidalgo H, et al.
J Mol Diagn
. 2021 Jun;
23(8):1000-1006.
PMID: 34082073
Toxoplasmosis can be a life-threatening infection, particularly during pregnancy and in immunocompromised patients. The biological diagnosis of toxoplasmosis is challenging and has been revolutionized by molecular detection methods. This article...
7.
Brenier-Pinchart M, Varlet-Marie E, Robert-Gangneux F, Filisetti D, Guitard J, Sterkers Y, et al.
PLoS One
. 2021 Feb;
16(2):e0246802.
PMID: 33596222
Introduction: Toxoplasma-PCR is essential to diagnose ocular, cerebral, disseminated and congenital toxoplasmosis. This multicenter study evaluated the impact of sample storage duration at +4°C on PCR assay performances in order...
8.
Yagoubat A, Corrales R, Bastien P, Leveque M, Sterkers Y
Trends Parasitol
. 2020 Jul;
36(9):745-760.
PMID: 32703742
Gene editing in trypanosomatids has long been proven difficult. The development of CRISPR-Cas9 has improved this issue, opening the way to a better understanding of biological processes and drug-resistance mechanisms,...
9.
Pasquier G, Azoury V, Sasso M, Laroche L, Varlet-Marie E, Houze S, et al.
Malar J
. 2020 May;
19(1):179.
PMID: 32393251
Background: Rapid diagnostic tests (RDTs) detecting the histidine-rich protein 2 (PfHRP2) have a central position for the management of Plasmodium falciparum infections. Yet, variable detection of certain targeted motifs, low...
10.
Leveque M, Battery E, Delaunay P, Lmimouni B, Aoun K, LOllivier C, et al.
PLoS Negl Trop Dis
. 2020 Mar;
14(3):e0008139.
PMID: 32210438
Background: Zoonotic visceral leishmaniasis (VL) is endemic in the Mediterranean basin. However, large-scale comparative analyses of the commercial kits for the serological diagnosis of this neglected disease are lacking. This...