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Patrick Adams

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Articles 29
Citations 186
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Recent Articles
1.
Konold P, Monrroy L, Bellisario A, Filipe D, Adams P, Alvarez R, et al.
Nat Methods . 2024 Jul; 21(9):1608-1611. PMID: 38969722
Detecting microsecond structural perturbations in biomolecules has wide relevance in biology, chemistry and medicine. Here we show how MHz repetition rates at X-ray free-electron lasers can be used to produce...
2.
Martin A, Adams P, Binns J
J Appl Crystallogr . 2024 Jun; 57(Pt 3):877-884. PMID: 38846774
The pair angle distribution function (PADF) is a three- and four-atom correlation function that characterizes the local angular structure of disordered materials, particles or nanocrystalline materials. The PADF can be...
3.
Adams P, Greaves T, Martin A
IUCrJ . 2024 Jun; 11(Pt 4):538-555. PMID: 38842120
Crystallography is a quintessential method for determining the atomic structure of crystals. The most common implementation of crystallography uses single crystals that must be of sufficient size, typically tens of...
4.
Paporakis S, Brown S, Darmanin C, Seibt S, Adams P, Hassett M, et al.
J Chem Phys . 2024 Jan; 160(2). PMID: 38189602
Monoolein-based liquid crystal phases are established media that are researched for various biological applications, including drug delivery. While water is the most common solvent for self-assembly, some ionic liquids (ILs)...
5.
Konold P, You T, Bielecki J, Valerio J, Kloos M, Westphal D, et al.
IUCrJ . 2023 Sep; 10(Pt 6):662-670. PMID: 37721770
X-ray free-electron lasers (XFELs) can probe chemical and biological reactions as they unfold with unprecedented spatial and temporal resolution. A principal challenge in this pursuit involves the delivery of samples...
6.
Wells D, Berntsen P, Balaur E, Kewish C, Adams P, Aquila A, et al.
J Synchrotron Radiat . 2022 May; 29(Pt 3):602-614. PMID: 35510993
Serial crystallography of membrane proteins often employs high-viscosity injectors (HVIs) to deliver micrometre-sized crystals to the X-ray beam. Typically, the carrier medium is a lipidic cubic phase (LCP) media, which...
7.
Berntsen P, Darmanin C, Balaur E, Flueckiger L, Kozlov A, Roque F, et al.
J Colloid Interface Sci . 2022 Jan; 611:588-598. PMID: 34973655
Continuous flow injection is a key technology for serial crystallography measurements of protein crystals suspended in the lipidic cubic phase (LCP). To date, there has been little discussion in the...
8.
El-Deeb M, Adams P, Schneider A, Salcedo-Arellano M, Tassone F, Hagerman R
J Mol Genet (Isleworth) . 2019 Apr; 1(1). PMID: 31032490
Fragile X-associated tremor/ataxia syndrome (FXTAS) affects individuals with 55-200 CGG repeats (premutation) in the 5'-untranslated region of the gene. FXTAS is a progressive neurodegenerative disorder associated with an action tremor,...
9.
Nutt C, Adams P
Lancet . 2017 Jun; 389(10079):1595-1596. PMID: 28593839
No abstract available.
10.
Adams P
Lancet . 2016 Apr; 387(10028):1605-6. PMID: 27116058
No abstract available.