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Patrick A Kupelian

Explore the profile of Patrick A Kupelian including associated specialties, affiliations and a list of published articles. Areas
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Articles 144
Citations 3556
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Recent Articles
11.
Nickols N, Ganapathy E, Nguyen C, Kane N, Lin L, Diaz-Perez S, et al.
Prostate Cancer Prostatic Dis . 2020 Jul; 24(1):135-139. PMID: 32647353
Background: Hundreds of ongoing clinical trials combine radiation therapy, mostly delivered as stereotactic body radiotherapy (SBRT), with immune checkpoint blockade. However, our understanding of the effect of radiotherapy on the...
12.
Parikh N, Kishan A, Kane N, Diaz-Perez S, Ganapathy E, Nazarian R, et al.
Int J Radiat Oncol Biol Phys . 2020 Jun; 108(4):930-935. PMID: 32562839
Purpose: This study aimed to evaluate the feasibility and safety of prostate stereotactic body radiation therapy (SBRT) neoadjuvant to radical prostatectomy (RP) in a phase 1 trial. The primary endpoint...
13.
Dang A, Levin-Epstein R, Shabsovich D, Cao M, King C, Chu F, et al.
Adv Radiat Oncol . 2020 Jun; 5(3):404-411. PMID: 32529134
Purpose: To establish the safety and efficacy of gantry-mounted linear accelerator-based stereotactic body radiation therapy (SBRT) for low- and intermediate-risk prostate cancer. Methods: We pooled 921 patients enrolled on 7...
14.
Valle L, Ruan D, Dang A, Levin-Epstein R, Patel A, Weidhaas J, et al.
Front Oncol . 2020 Jun; 10:786. PMID: 32509582
Dosimetric predictors of toxicity after Stereotactic Body Radiation Therapy (SBRT) are not well-established. We sought to develop a multivariate model that predicts Common Terminology Criteria for Adverse Events (CTCAE) late...
15.
Levin-Epstein R, Qiao-Guan G, Juarez J, Shen Z, Steinberg M, Ruan D, et al.
Front Oncol . 2020 May; 10:539. PMID: 32373529
To assess the optimal planning target volume (PTV) margins for stereotactic body radiotherapy (SBRT) of prostate cancer based on inter- and intra-fractional prostate motion determined from daily image guidance. Two...
16.
Ritter M, Kupelian P, Petereit D, Lawton C, Anger N, Geye H, et al.
Pract Radiat Oncol . 2020 Mar; 10(5):345-353. PMID: 32169590
Purpose: This phase I/II, multi-institutional trial explored the tolerance and efficacy of stepwise increasing hypofractionation (HPFX) radiation therapy regimens for fraction sizes up to 4.3 Gy in localized prostate cancer....
17.
Kishan A, Chu F, King C, Seiferheld W, Spratt D, Tran P, et al.
Eur Urol . 2019 Nov; 77(2):201-208. PMID: 31718822
Background: The importance of local failure (LF) after treatment of high-grade prostate cancer (PCa) with definitive radiotherapy (RT) remains unknown. Objective: To evaluate the clinical implications of LF after definitive...
18.
Wang C, Kishan A, Yu J, Raldow A, King C, Iwamoto K, et al.
Adv Radiat Oncol . 2019 Nov; 4(4):738-747. PMID: 31673667
Purpose: Second malignancies (SMs) after radiation therapy are rare but serious sequelae of treatment. This study investigates whether radiation therapy use is associated with changes in baseline SM risk. Methods...
19.
Wang C, Raldow A, Nickols N, Nguyen P, Spratt D, Dess R, et al.
Eur Urol Oncol . 2019 Aug; 4(2):327-330. PMID: 31411981
Multiple randomized trials have shown a survival benefit to long durations of androgen deprivation therapy (ADT) in patients with Gleason grade group (GG) 4-5 (ie, Gleason score 8-10) prostate cancer...
20.
Jiang N, Dang A, Yuan Y, Chu F, Shabsovich D, King C, et al.
Int J Radiat Oncol Biol Phys . 2019 Jul; 105(3):628-636. PMID: 31276777
Purpose: Understanding prostate-specific antigen (PSA) kinetics after radiation therapy plays a large role in the management of patients with prostate cancer (PCa). This is particularly true in establishing expectations regarding...