Patricia S Langan
Overview
Explore the profile of Patricia S Langan including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
15
Citations
140
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Paugh B, Baranyi L, Roy A, He H, Harris L, Cole K, et al.
Sci Rep
. 2021 Jan;
11(1):389.
PMID: 33431989
Lentiviral vectors (LV) have emerged as a robust technology for therapeutic gene delivery into human cells as advanced medicinal products. As these products are increasingly commercialized, there are concomitant demands...
2.
Langan P, Vandavasi V, Kopec W, Sullivan B, Afonne P, Weiss K, et al.
IUCrJ
. 2020 Sep;
7(Pt 5):835-843.
PMID: 32939275
Protein dynamics are essential to function. One example of this is the various gating mechanisms within ion channels, which are transmembrane proteins that act as gateways into the cell. Typical...
3.
Langan P, Sullivan B, Weiss K, Coates L
Acta Crystallogr D Struct Biol
. 2020 Feb;
76(Pt 2):118-123.
PMID: 32038042
The amino-acid sequence of the Toho-1 β-lactamase contains several conserved residues in the active site, including Ser70, Lys73, Ser130 and Glu166, some of which coordinate a catalytic water molecule. This...
4.
Sullivan B, Langan P, Archibald R, Coates L, Vadavasi V, Lynch V
IEEE ACM Int Symp Clust Cloud Grid Comput
. 2019 Dec;
2019:549-555.
PMID: 31886471
Crystallography is the powerhouse technique for molecular structure determination, with applications in fields ranging from energy storage to drug design. Accurate structure determination, however, relies partly on determining the precise...
5.
Sullivan B, Archibald R, Azadmanesh J, Vandavasi V, Langan P, Coates L, et al.
J Appl Crystallogr
. 2019 Aug;
52(Pt 4):854-863.
PMID: 31396028
Neutron crystallography offers enormous potential to complement structures from X-ray crystallography by clarifying the positions of low- elements, namely hydrogen. Macromolecular neutron crystallography, however, remains limited, in part owing to...
6.
Dajnowicz S, Langan P, Weiss K, Ivanov I, Kovalevsky A
IUCrJ
. 2019 Jul;
6(Pt 4):781.
PMID: 31318360
[This retracts the article DOI: 10.1107/S2052252519005761.].
7.
Dajnowicz S, Langan P, Weiss K, Ivanov I, Kovalevsky A
IUCrJ
. 2019 Jul;
6(Pt 4):619-629.
PMID: 31316806
Martensitic transformations are the first-order crystal-to-crystal phase transitions that occur mostly in materials such as steel, alloys and ceramics, thus having many technological applications. These phase transitions are rarely observed...
8.
Langan P, Vandavasi V, Sullivan B, Harp J, Weiss K, Coates L
Acta Crystallogr F Struct Biol Commun
. 2019 Jun;
75(Pt 6):435-438.
PMID: 31204690
The mechanism by which potassium ions are transported through ion channels is currently being investigated by several groups using many different techniques. Clarification of the location of water molecules during...
9.
Sullivan B, Archibald R, Langan P, Dobbek H, Bommer M, McFeeters R, et al.
Acta Crystallogr D Struct Biol
. 2018 Nov;
74(Pt 11):1085-1095.
PMID: 30387767
Neutron crystallography is a powerful technique for directly visualizing the locations of H atoms in biological macromolecules. This information has provided key new insights into enzyme mechanisms, ligand binding and...
10.
Langan P, Vandavasi V, Weiss K, Afonine P, El Omari K, Duman R, et al.
Nat Commun
. 2018 Nov;
9(1):4540.
PMID: 30382100
Potassium ion channels utilize a highly selective filter to rapidly transport K ions across cellular membranes. This selectivity filter is composed of four binding sites which display almost equal electron...