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Patricia M Desmond

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Articles 107
Citations 5929
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Recent Articles
1.
Ngo A, Liu L, Lariviere S, Kebets V, Fett S, Weber C, et al.
bioRxiv . 2025 Jan; PMID: 39868179
Temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) is associated with a complex genetic architecture, but the translation from genetic risk factors to brain vulnerability remains unclear. Here, we examined associations...
2.
Nguyen A, Sormani M, Horakova D, Havrdova E, Barnett M, De Stefano N, et al.
Mult Scler Relat Disord . 2024 Nov; 92():106148. PMID: 39536619
Background: Few studies on multiple sclerosis (MS) have explored the variability of percentage brain volume change (PBVC) measurements obtained from different clinical MRIs. In a retrospective multicentre cohort study, we...
3.
Lui E, Venkatraman V, Finch S, Chua M, Li T, Sutton B, et al.
Brain Commun . 2024 Sep; 6(5):fcae307. PMID: 39318783
Dementia is a burgeoning global problem. Novel magnetic resonance imaging (MRI) metrics beyond volumetry may bring new insight and aid clinical trial evaluation of interventions early in the Alzheimer's disease...
4.
Kataike V, Desmond P, Steward C, Mitchell P, Davey C, Yassi N, et al.
Neuroradiology . 2024 Aug; 66(12):2233-2242. PMID: 39172165
Purpose: For nearly half of patients who undergo Endovascular Thrombectomy following ischemic stroke, successful recanalisation does not guarantee a good outcome. Understanding the underlying tissue changes in the infarct tissue...
5.
Chen J, Ngo A, Rodriguez-Cruces R, Royer J, Caligiuri M, Gambardella A, et al.
bioRxiv . 2024 Mar; PMID: 38496668
Objectives: Temporal lobe epilepsy (TLE) is commonly associated with mesiotemporal pathology and widespread alterations of grey and white matter structures. Evidence supports a progressive condition although the temporal evolution of...
6.
Yogendrakumar V, Churilov L, Mitchell P, Kleinig T, Yassi N, Thijs V, et al.
Neurology . 2023 Mar; 100(18):e1900-e1911. PMID: 36878701
Background And Objectives: The safety and efficacy of tenecteplase (TNK) in patients with tandem lesion (TL) stroke is unknown. We performed a comparative analysis of TNK and alteplase in patients...
7.
Yogendrakumar V, Churilov L, Guha P, Beharry J, Mitchell P, Kleinig T, et al.
Stroke . 2023 Feb; 54(3):706-714. PMID: 36727510
Background: Intracranial occlusion site, contrast permeability, and clot burden are thrombus characteristics that influence alteplase-associated reperfusion. In this study, we assessed the reperfusion efficacy of tenecteplase and alteplase in subgroups...
8.
Yogendrakumar V, Beharry J, Churilov L, Alidin K, Ugalde M, Pesavento L, et al.
Ann Neurol . 2022 Nov; 93(3):489-499. PMID: 36394101
Objective: Tenecteplase improves reperfusion compared to alteplase in patients with large vessel occlusions. To determine whether this improvement varies across the spectrum of thrombolytic agent to reperfusion assessment times, we...
9.
Chin K, Hijazi Z, Churilov L, Gajamange S, Desmond P, Villemagne V, et al.
Parkinsonism Relat Disord . 2022 Oct; 104:68-71. PMID: 36252391
Introduction: Cerebral microbleeds (CMB) are associated with cognitive impairment and hypertensive or cerebral amyloid angiopathy. The pathophysiology and clinical significance of CMB in dementia with Lewy bodies (DLB) are not...
10.
Lariviere S, Royer J, Rodriguez-Cruces R, Paquola C, Caligiuri M, Gambardella A, et al.
Nat Commun . 2022 Jul; 13(1):4320. PMID: 35896547
Epilepsy is associated with genetic risk factors and cortico-subcortical network alterations, but associations between neurobiological mechanisms and macroscale connectomics remain unclear. This multisite ENIGMA-Epilepsy study examined whole-brain structural covariance networks...