Patricia Desmond
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Explore the profile of Patricia Desmond including associated specialties, affiliations and a list of published articles.
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70
Citations
1961
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Recent Articles
1.
Ripart M, Spitzer H, Williams L, Walger L, Chen A, Napolitano A, et al.
JAMA Neurol
. 2025 Feb;
PMID: 39992650
Importance: A leading cause of surgically remediable, drug-resistant focal epilepsy is focal cortical dysplasia (FCD). FCD is challenging to visualize and often considered magnetic resonance imaging (MRI) negative. Existing automated...
2.
Ayton S, Barton D, Brew B, Brodtmann A, Clarnette R, Desmond P, et al.
JAMA Neurol
. 2024 Nov;
82(1):11-18.
PMID: 39495531
Importance: Interventions that substantially slow neurodegeneration are needed to address the growing burden of Alzheimer disease (AD) to societies worldwide. Elevated brain iron observed in AD has been associated with...
3.
Yogendrakumar V, Beharry J, Churilov L, Pesavento L, Alidin K, Ugalde M, et al.
Neurology
. 2024 Mar;
102(7):e209166.
PMID: 38502892
Background And Objectives: Early treatment with intravenous alteplase increases the probability of lytic-induced reperfusion in large vessel occlusion (LVO) patients. The relationship of tenecteplase-induced reperfusion and the timing of thrombolytic...
4.
Vidyasagar R, Fazollahi A, Desmond P, Moffat B, Bush A, Ayton S
J Neuroimaging
. 2024 Jan;
34(2):224-231.
PMID: 38174904
Background And Purpose: Magnetic resonance spectroscopy (MRS) measures neurochemicals in vivo. Glutathione (GSH) is a neuroprotective chemical shown to vary significantly in patients with Alzheimer's disease (AD). This work investigates...
5.
Ravanfar P, Rushmore R, Lyall A, Cropley V, Makris N, Desmond P, et al.
J Eat Disord
. 2023 Aug;
11(1):142.
PMID: 37605216
Background: Anorexia nervosa (AN) is a potentially fatal psychiatric condition, associated with structural brain changes such as gray matter volume loss. The pathophysiological mechanisms for these changes are not yet...
6.
Pham J, Gan C, Dabboucy J, Stella D, Dowling R, Yan B, et al.
Int J Stroke
. 2023 Jun;
18(10):1228-1237.
PMID: 37260232
Background: Following reperfusion treatment in ischemic stroke, computed tomography (CT) imaging at 24 h is widely used to assess radiological outcomes. Even without visible hyperattenuation, occult angiographic contrast may persist...
7.
Mitchell P, Lee S, Yoo P, Morokoff A, Sharma R, Williams D, et al.
JAMA Neurol
. 2023 Jan;
80(3):270-278.
PMID: 36622685
Importance: Brain-computer interface (BCI) implants have previously required craniotomy to deliver penetrating or surface electrodes to the brain. Whether a minimally invasive endovascular technique to deliver recording electrodes through the...
8.
Ravanfar P, Syeda W, Jayaram M, Rushmore R, Moffat B, Lin A, et al.
Schizophrenia (Heidelb)
. 2022 Oct;
8(1):86.
PMID: 36289238
Brain iron is central to dopaminergic neurotransmission, a key component in schizophrenia pathology. Iron can also generate oxidative stress, which is one proposed mechanism for gray matter volume reduction in...
9.
Spitzer H, Ripart M, Whitaker K, DArco F, Mankad K, Chen A, et al.
Brain
. 2022 Aug;
145(11):3859-3871.
PMID: 35953082
One outstanding challenge for machine learning in diagnostic biomedical imaging is algorithm interpretability. A key application is the identification of subtle epileptogenic focal cortical dysplasias (FCDs) from structural MRI. FCDs...
10.
Ng F, Churilov L, Yassi N, Kleinig T, Thijs V, Wu T, et al.
Neurology
. 2021 Dec;
98(8):e790-e801.
PMID: 34906976
Background And Objectives: The relevance of impaired microvascular tissue-level reperfusion despite complete upstream macrovascular angiographic reperfusion (no-reflow) in human stroke remains controversial. We investigated the prevalence and clinical-radiologic features of...