Patrice Vachette
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Explore the profile of Patrice Vachette including associated specialties, affiliations and a list of published articles.
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50
Citations
1226
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Recent Articles
1.
Trewhella J, Vachette P, Larsen A
IUCrJ
. 2024 Jul;
11(Pt 5):762-779.
PMID: 38989800
Stimulated by informal conversations at the XVII International Small Angle Scattering (SAS) conference (Traverse City, 2017), an international team of experts undertook a round-robin exercise to produce a large dataset...
2.
Brookes E, Rocco M, Vachette P, Trewhella J
J Appl Crystallogr
. 2023 Aug;
56(Pt 4):910-926.
PMID: 37555230
By providing predicted protein structures from nearly all known protein sequences, the artificial intelligence program AlphaFold (AF) is having a major impact on structural biology. While a stunning accuracy has...
3.
Perez J, Thureau A, Vachette P
Methods Enzymol
. 2022 Nov;
677:221-249.
PMID: 36410950
A monodispersed and ideal solution is a key requirement of BioSAXS to allow one to extract structural information from the recorded pattern. On-line size exclusion chromatography (SEC) marked a major...
4.
Trewhella J, Vachette P, Bierma J, Blanchet C, Brookes E, Chakravarthy S, et al.
Acta Crystallogr D Struct Biol
. 2022 Nov;
78(Pt 11):1315-1336.
PMID: 36322416
Through an expansive international effort that involved data collection on 12 small-angle X-ray scattering (SAXS) and four small-angle neutron scattering (SANS) instruments, 171 SAXS and 76 SANS measurements for five...
5.
Leger C, Pitard I, Sadi M, Carvalho N, Brier S, Mechaly A, et al.
BMC Biol
. 2022 Aug;
20(1):176.
PMID: 35945584
Background: Calmodulin (CaM) is an evolutionarily conserved eukaryotic multifunctional protein that functions as the major sensor of intracellular calcium signaling. Its calcium-modulated function regulates the activity of numerous effector proteins...
6.
Voegele A, Sadi M, OBrien D, Gehan P, Raoux-Barbot D, Davi M, et al.
Adv Sci (Weinh)
. 2021 May;
8(9):2003630.
PMID: 33977052
The molecular mechanisms and forces involved in the translocation of bacterial toxins into host cells are still a matter of intense research. The adenylate cyclase (CyaA) toxin from displays a...
7.
Voegele A, OBrien D, Subrini O, Sapay N, Cannella S, Enguene V, et al.
Pathog Dis
. 2018 Nov;
76(8).
PMID: 30452651
The adenylate cyclase toxin (CyaA) is a multi-domain protein secreted by Bordetella pertussis, the causative agent of whooping cough. CyaA is involved in the early stages of respiratory tract colonization...
8.
OBrien D, Perez A, Karst J, Cannella S, Enguene V, Hessel A, et al.
Toxicon
. 2018 Jan;
149:37-44.
PMID: 29337218
The adenylate cyclase toxin (CyaA) plays an essential role in the early stages of respiratory tract colonization by Bordetella pertussis, the causative agent of whooping cough. Once secreted, CyaA invades...
9.
OBrien D, Durand D, Voegele A, Hourdel V, Davi M, Chamot-Rooke J, et al.
PLoS Biol
. 2017 Dec;
15(12):e2004486.
PMID: 29287065
Once translocated into the cytosol of target cells, the catalytic domain (AC) of the adenylate cyclase toxin (CyaA), a major virulence factor of Bordetella pertussis, is potently activated by binding...
10.
Perez J, Vachette P
Adv Exp Med Biol
. 2017 Dec;
1009:183-199.
PMID: 29218560
A monodispersed and ideal solution is a central (unique?) requirement of SAXS to allow one to extract structural information from the recorded pattern. On-line Size Exclusion Chromatography (SEC) marked a...