Pascal Lapierre
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Explore the profile of Pascal Lapierre including associated specialties, affiliations and a list of published articles.
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97
Citations
2040
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Recent Articles
1.
Weeber P, Singh N, Lapierre P, Mingle L, Wroblewski D, Nazarian E, et al.
J Clin Microbiol
. 2024 Mar;
62(4):e0130523.
PMID: 38511938
The unprecedented precision and resolution of whole genome sequencing (WGS) can provide definitive identification of infectious agents for epidemiological outbreak tracking. WGS approaches, however, are frequently impeded by low pathogen...
2.
Lemieux J, Huang W, Hill N, Cerar T, Freimark L, Hernandez S, et al.
PLoS Pathog
. 2023 Aug;
19(8):e1011243.
PMID: 37651316
Lyme disease is the most common vector-borne disease in North America and Europe. The clinical manifestations of Lyme disease vary based on the genospecies of the infecting Borrelia burgdorferi spirochete,...
3.
Shea J, Halse T, Modestil H, Kearns C, Fowler R, Da Costa-Carter C, et al.
Tuberculosis (Edinb)
. 2023 Aug;
142:102380.
PMID: 37543009
Whole-genome sequencing (WGS) can predict drug resistance and antimicrobial susceptibility in Mycobacterium tuberculosis complex (MTBC) and has shown promise in partially replacing culture-based phenotypic drug susceptibility testing (pDST). We performed...
4.
Murphy S, Smith C, Lapierre P, Shea J, Patel K, Halse T, et al.
Front Public Health
. 2023 Jul;
11:1206056.
PMID: 37457262
complex (MTBC) infections are treated with combinations of antibiotics; however, these regimens are not as efficacious against multidrug and extensively drug resistant MTBC. Phenotypic (growth-based) drug susceptibility testing on slow...
5.
Fitzgerald D, Stringer A, Smith C, Lapierre P, Wade J
mBio
. 2023 Apr;
14(3):e0253522.
PMID: 37067422
Genome-scale analyses have revealed many transcription factor binding sites within, rather than upstream of, genes, raising questions as to the function of these binding sites. Here, we use complementary approaches...
6.
Lemieux J, Huang W, Hill N, Cerar T, Freimark L, Hernandez S, et al.
bioRxiv
. 2023 Mar;
PMID: 36909473
Lyme disease is the most common vector-borne disease in North America and Europe. The clinical manifestations of Lyme disease vary based on the genospecies of the infecting spirochete, but the...
7.
Fitzgerald D, Stringer A, Smith C, Lapierre P, Wade J
bioRxiv
. 2023 Feb;
PMID: 36798257
Importance: Recent studies have revealed large numbers of transcription factor binding sites within the genes of bacteria. The function, if any, of the vast majority of these binding sites has...
8.
Musser E, Smith C, Halse T, Kohlerschmidt D, Rourke A, Fiero A, et al.
Front Microbiol
. 2022 Oct;
13:992610.
PMID: 36299734
Nontuberculous mycobacteria (NTM) are environmental bacteria commonly found in soil and water in almost every part of the world. While usually non-pathogenic, they can cause acute respiratory and cutaneous infections...
9.
Lapierre P, Alvarez F
Front Immunol
. 2022 Oct;
13:1025343.
PMID: 36248826
Two types of autoimmune hepatitis (AIH) are recognized; AIH-1 is characterized by the presence of anti-nuclear and/or anti-smooth muscle autoantibodies, while AIH-2 is associated with the presence of anti-Liver kidney...
10.
Prussing C, Southwick K, Snavely E, Kidney A, Randall L, Sossei A, et al.
Diagn Microbiol Infect Dis
. 2022 Aug;
104(2):115765.
PMID: 35932600
In 2017, the New York State Department of Health investigated a large Klebsiella pneumoniae outbreak in a health care facility. A retrospective analysis was conducted to compare the use of...