Pascal Knuefermann
Overview
Explore the profile of Pascal Knuefermann including associated specialties, affiliations and a list of published articles.
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43
Citations
881
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0
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Recent Articles
1.
Boehm O, Rohner M, Ehrentraut H, Guenther U, Meyer R, Knuefermann P, et al.
Life Sci
. 2019 Nov;
240:117081.
PMID: 31756342
Background And Goal Of The Study: Pulmonary inflammation, increased vascular permeability, and pulmonary edema, occur in response to primary pulmonary infections like pneumonia but are also evident in endotoxemia or...
2.
Kowark A, Adam C, Ahrens J, Bajbouj M, Bollheimer C, Borowski M, et al.
BMJ Open
. 2018 Oct;
8(10):e023609.
PMID: 30341135
Introduction: Hip fracture surgery is associated with high in-hospital and 30-day mortality rates and serious adverse patient outcomes. Evidence from randomised controlled trials regarding effectiveness of spinal versus general anaesthesia...
3.
Hilbert T, Markowski P, Frede S, Boehm O, Knuefermann P, Baumgarten G, et al.
J Cell Mol Med
. 2018 Apr;
22(7):3397-3407.
PMID: 29671939
We previously demonstrated that pre-conditioning with CpG oligonucleotide (ODN) 1668 induces quick up-regulation of gene expression 3 hours post-murine myocardial ischaemia/reperfusion (I/R) injury, terminating inflammatory processes that sustain I/R injury....
4.
Krieg S, Voigt F, Knuefermann P, Kirschning C, Plesnila N, Ringel F
Front Neurol
. 2017 Sep;
8:455.
PMID: 28912751
Danger-associated molecular patterns are released by damaged cells and trigger neuroinflammation through activation of non-specific pattern recognition receptors, e.g., toll-like receptors (TLRs). Since the role of TLR2 and 4 after...
5.
Bualeong T, Kebir S, Hof D, Goelz L, Graewe M, Ehrentraut S, et al.
J Negat Results Biomed
. 2016 Apr;
15:9.
PMID: 27109115
Background: Toll-like receptors (TLRs) are involved in a variety of cardiovascular disorders, including septic cardiomyopathy, ischemia/reperfusion, heart failure, and cardiac hypertrophy. Previous research revealed that TLR4 promotes cardiac hypertrophy in...
6.
Muenster S, Bode C, Diedrich B, Jahnert S, Weisheit C, Steinhagen F, et al.
Life Sci
. 2015 Sep;
141:128-36.
PMID: 26382596
Aims: The incidence of secondary systemic fungal infections has sharply increased in bacterial septic patients. Antimycotics exhibit immunomodulatory properties, yet these effects are incompletely understood in secondary systemic fungal infections...
7.
Kim S, Wu S, Fang X, Neumann J, Eichhorn L, Schleifer G, et al.
Life Sci
. 2014 Dec;
119(1-2):1-8.
PMID: 25445440
Aims: Toll-like receptor (TLR)9 ligand CpG-oligodeoxynucleotide (CpG-ODN) exerts preconditioning in myocardial ischemia/reperfusion. We hypothesized a postconditioning effect of CpG-ODN in a murine closed-chest model of myocardial infarction. Materials And Methods:...
8.
Kim S, Heinze I, Schmiedel A, Baumgarten G, Knuefermann P, Hoeft A, et al.
Eur J Anaesthesiol
. 2014 Jan;
32(1):29-36.
PMID: 24384583
Background: Visualisation of a central venous catheter (CVC) with ultrasound is restricted to the internal jugular vein (IJV). CVC tip position is confirmed by chest radiography, intracardiac ECG or transoesophageal/transthoracic...
9.
Bode C, Diedrich B, Muenster S, Hentschel V, Weisheit C, Rommelsheim K, et al.
Int Immunopharmacol
. 2013 Nov;
18(1):27-34.
PMID: 24239744
The inflammatory response to pathogen-associated molecular patterns such as lipopolysaccharide (LPS) in sepsis is mediated via Toll-like receptors (TLRs). Since TLRs also trigger various immune functions, including phagocytosis, their modulation...
10.
Boehm O, Knuefermann P, Plueck J, Schwederski M, Ehrentraut H, Kebir S, et al.
J Inflamm (Lond)
. 2013 Nov;
10(1):33.
PMID: 24171786
Background: Bacteria such as Staphylococcus aureus induce myocardial dysfunction in vivo. To rectify conflicting evidence about the role of TLR2 signaling and cardiac dysfunction, we hypothesized that the specific TLR2...