Pascal Genin
Overview
Explore the profile of Pascal Genin including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
155
Followers
0
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Recent Articles
1.
MacGrogan G, Mathieu M, Poulet B, Penault-Llorca F, Vincent-Salomon A, Roger P, et al.
Ann Pathol
. 2014 Dec;
34(5):366-72.
PMID: 25439989
Biomarker assessment of breast cancer tumor samples is part of the routine workflow of pathology laboratories. International guidelines have recently been updated, with special regards to the pre-analytical steps that...
2.
Penault-Llorca F, Vincent-Salomon A, MacGrogan G, Roger P, Treilleux I, Valent A, et al.
Ann Pathol
. 2014 Dec;
34(5):352-65.
PMID: 25439988
International guidelines on HER2 determination in breast cancer have just been updated by the American Society of Clinical Oncology (ASCO) and College of American Pathologists (CAP), on the basis of...
3.
Chretien A, Harle A, Meyer-Lefebvre M, Rouyer M, Husson M, Ramacci C, et al.
Cancer Med
. 2013 Oct;
2(1):11-20.
PMID: 24133623
KRAS mutation detection represents a crucial issue in metastatic colorectal cancer (mCRC). The optimization of KRAS mutation detection delay enabling rational prescription of first-line treatment in mCRC including anti-EGFR-targeted therapy...
4.
Harle A, Busser B, Rouyer M, Harter V, Genin P, Leroux A, et al.
Virchows Arch
. 2013 Feb;
462(3):329-35.
PMID: 23400679
Many studies documented the influence of KRAS mutation status on the response of patients with metastatic colorectal cancer (mCRC) to anti-EGFR monoclonal antibodies. The COBAS 4800 KRAS is an assay...
5.
Harle A, Lion M, Lozano N, Husson M, Harter V, Genin P, et al.
Oncol Rep
. 2013 Jan;
29(3):1043-52.
PMID: 23314198
Phosphatidylinositol-3-kinases (PI3K) are essential for cell signaling, proliferation, differentiation and survival. The catalytic subunit of PI3K, encoded by the PIK3CA oncogene, is mutated in 18-45% of breast carcinomas. These mutations,...
6.
Maalouf T, Dolivet G, Angioi K, Leroux A, Genin P, George J
Ophthalmic Plast Reconstr Surg
. 2012 Jan;
28(1):30-4.
PMID: 22262287
Purpose: To assess lymph node invasion through the use of sentinel lymph node biopsy (SLNB) in conjunctival and eyelid tumor patients and ascertain the impact of this technique in therapeutic...
7.
Gauchotte G, Gauchotte E, Bressenot A, Verhaeghe J, Guillemin F, Leroux A, et al.
Ann Pathol
. 2011 Feb;
31(1):18-27.
PMID: 21349384
Introduction: Metaplastic carcinomas of the breast are rare and form a heterogenic group of tumors, characterized by the presence of squamous or sarcomatoid differentiation. Patient And Methods: In 23 cases,...
8.
Penault-Llorca F, Vincent-Salomon A, Bellocq J, Matthieu M, Grogan G, Treilleux I, et al.
Ann Pathol
. 2010 Nov;
30(5):357-73.
PMID: 21055523
In Europe, patients who may benefit from an HER2 targeted drug are currently selected by immunohistochemistry (IHC). In situ hybridization (ISH) techniques should be used for complementary assessment of ambiguous...
9.
Chergui F, Chretien A, Bouali S, Ramacci C, Rouyer M, Bastogne T, et al.
Clin Chem
. 2009 May;
55(7):1327-36.
PMID: 19443568
Background: Human epidermal growth factor receptor (HER) downstream signaling kinases have important effects on tumor response to anti-HER monoclonal antibodies and tyrosine kinase inhibitors. We validated an assay that uses...
10.
Monnet E, Marquant A, Genin P, Mauny F, Carbillet J
Eur J Obstet Gynecol Reprod Biol
. 2004 Apr;
113(2):234-9.
PMID: 15063967
Objective: After a HGSIL cervical smear, to appraise the diagnostic and treatment modalities by comparing with national recommendations. Study Design: A clinical audit concerning 444 women with a HGSIL cervical...