Pascal Bouffard
Overview
Explore the profile of Pascal Bouffard including associated specialties, affiliations and a list of published articles.
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16
Citations
2253
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Recent Articles
11.
Bellin D, Ferrarini A, Chimento A, Kaiser O, Levenkova N, Bouffard P, et al.
BMC Genomics
. 2009 Nov;
10:555.
PMID: 19930683
Background: The next generation sequencing technologies provide new options to characterize the transcriptome and to develop affordable tools for functional genomics. We describe here an innovative approach for this purpose...
12.
Han T, Manoharan A, Harkins T, Bouffard P, Fitzpatrick C, Chu D, et al.
Proc Natl Acad Sci U S A
. 2009 Oct;
106(44):18674-9.
PMID: 19846761
Endogenous small interfering RNAs (endo-siRNAs) regulate diverse gene expression programs in eukaryotes by either binding and cleaving mRNA targets or mediating heterochromatin formation; however, the mechanisms of endo-siRNA biogenesis, sorting,...
13.
Wiseman R, Karl J, Bimber B, OLeary C, Lank S, Tuscher J, et al.
Nat Med
. 2009 Oct;
15(11):1322-6.
PMID: 19820716
Major histocompatibility complex (MHC) genetics dictate adaptive cellular immune responses, making robust MHC genotyping methods essential for studies of infectious disease, vaccine development and transplantation. Nonhuman primates provide essential preclinical...
14.
Quinn N, Levenkova N, Chow W, Bouffard P, Boroevich K, Knight J, et al.
BMC Genomics
. 2008 Aug;
9:404.
PMID: 18755037
Background: With a whole genome duplication event and wealth of biological data, salmonids are excellent model organisms for studying evolutionary processes, fates of duplicated genes and genetic and physiological processes...
15.
Yeager M, Xiao N, Hayes R, Bouffard P, Desany B, Burdett L, et al.
Hum Genet
. 2008 Aug;
124(2):161-70.
PMID: 18704501
Recently, genome-wide association studies have identified loci across a segment of chromosome 8q24 (128,100,000-128,700,000) associated with the risk of breast, colon and prostate cancers. At least three regions of 8q24...
16.
Sugarbaker D, Richards W, Gordon G, Dong L, De Rienzo A, Maulik G, et al.
Proc Natl Acad Sci U S A
. 2008 Feb;
105(9):3521-6.
PMID: 18303113
Cancers arise by the gradual accumulation of mutations in multiple genes. We now use shotgun pyrosequencing to characterize RNA mutations and expression levels unique to malignant pleural mesotheliomas (MPMs) and...