Parthasaradhireddy Tanguturi
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Explore the profile of Parthasaradhireddy Tanguturi including associated specialties, affiliations and a list of published articles.
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12
Citations
57
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Recent Articles
1.
Duron D, Tanguturi P, Campbell C, Chou K, Bejarano P, Gabriel K, et al.
Sci Rep
. 2024 Jun;
14(1):14715.
PMID: 38926482
Opioids are the gold standard for the treatment of chronic pain but are limited by adverse side effects. In our earlier work, we showed that Heat shock protein 90 (Hsp90)...
2.
Tanguturi P, Streicher J
Front Pharmacol
. 2023 Mar;
14:1056402.
PMID: 36937877
Alzheimer's disease (AD) is a complex neurological disorder characterized by accumulation of amyloid plaques and neurofibrillary tangles. Long term investigation of AD pathogenesis suggests that β-site amyloid precursor protein [APP]...
3.
Szabo L, Tanguturi P, Goodman H, Sprober S, Liu C, Al-Obeidi F, et al.
ACS Med Chem Lett
. 2023 Feb;
14(2):163-170.
PMID: 36793431
Acute and chronic pain is often treated with opioids despite the negative side effects of constipation, physical dependence, respiratory depression, and overdose. The misuse of opioid analgesics has given rise...
4.
Stefanucci A, Minosi P, Pieretti S, Tanguturi P, Molnar G, Scioli G, et al.
ACS Chem Neurosci
. 2023 Jan;
14(3):506-515.
PMID: 36651179
The discovery of efficacious and safe analgesics with reduced side effects is the foremost challenge in the pain field. In this work, we report the and evaluation of linear and...
5.
Stefanucci A, Della Valle A, Scioli G, Marinaccio L, Pieretti S, Minosi P, et al.
ACS Med Chem Lett
. 2022 Nov;
13(11):1707-1714.
PMID: 36385929
Peripherally active tetrapeptides as selective κ opioid receptor (KOR) agonists have been prepared in good overall yields and high purity following solid-phase peptide synthesis via Fmoc protection strategy. Structural modifications...
6.
Tanguturi P, Pathak V, Zhang S, Moukha-Chafiq O, Augelli-Szafran C, Streicher J
Molecules
. 2022 Mar;
27(6).
PMID: 35335399
There was an error in the original publication [...].
7.
Apostol C, Bernard K, Tanguturi P, Molnar G, Bartlett M, Szabo L, et al.
Front Drug Discov (Lausanne)
. 2022 Mar;
1.
PMID: 35237767
There is an unmet clinical need for curative therapies to treat neurodegenerative disorders. Most mainstay treatments currently on the market only alleviate specific symptoms and do not reverse disease progression....
8.
Kaushal K, Tyagi A, Karapurkar J, Kim E, Tanguturi P, Kim K, et al.
Int J Mol Sci
. 2022 Jan;
23(2).
PMID: 35055037
The osteoblast differentiation capacity of mesenchymal stem cells must be tightly regulated, as inadequate bone mineralization can lead to osteoporosis, and excess bone formation can cause the heterotopic ossification of...
9.
Tanguturi P, Pathak V, Zhang S, Moukha-Chafiq O, Augelli-Szafran C, Streicher J
Molecules
. 2021 Nov;
26(21).
PMID: 34771099
The delta opioid receptor (DOR) is a crucial receptor system that regulates pain, mood, anxiety, and similar mental states. DOR agonists, such as SNC80, and DOR-neutral antagonists, such as naltrindole,...
10.
Apostol C, Tanguturi P, Szabo L, Varela D, Gilmartin T, Streicher J, et al.
Molecules
. 2021 Aug;
26(16).
PMID: 34443519
The search for efficacious treatment of neurodegenerative and progressive neuroinflammatory diseases continues, as current therapies are unable to halt or reverse disease progression. PACAP represents one potential therapeutic that provides...