Papiya Choudhury
Overview
Explore the profile of Papiya Choudhury including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
588
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Recent Articles
1.
Shanmugam S, Kanner S, Zou X, Amarh E, Choudhury P, Soni R, et al.
bioRxiv
. 2024 Sep;
PMID: 39345403
Protein posttranslational modification with distinct polyubiquitin linkage chains is a critical component of the 'ubiquitin code' that universally regulates protein expression and function to control biology. Functional consequences of diverse...
2.
Morgenstern T, Darko-Boateng A, Afriyie E, Shanmugam S, Zhou X, Choudhury P, et al.
bioRxiv
. 2024 Jun;
PMID: 38854018
Targeted recruitment of E3 ubiquitin ligases to degrade traditionally undruggable proteins is a disruptive paradigm for developing new therapeutics. Two salient limitations are that <2% of the ~600 E3 ligases...
3.
Blomquist V, Niu J, Choudhury P, Al Saneh A, Colecraft H, Ahern C
Mol Ther Nucleic Acids
. 2023 Oct;
34:102032.
PMID: 37842167
Disease-causing premature termination codons (PTCs) individually disrupt the functional expression of hundreds of genes and represent a pernicious clinical challenge. In the heart, loss-of-function mutations in the hERG potassium channel...
4.
Morgenstern T, Nirwan N, Hernandez-Ochoa E, Bibollet H, Choudhury P, Laloudakis Y, et al.
Nat Commun
. 2022 Dec;
13(1):7556.
PMID: 36494348
Ca influx through high-voltage-activated calcium channels (HVACCs) controls diverse cellular functions. A critical feature enabling a singular signal, Ca influx, to mediate disparate functions is diversity of HVACC pore-forming α...
5.
Kanner S, Shuja Z, Choudhury P, Jain A, Colecraft H
Nat Methods
. 2020 Nov;
17(12):1245-1253.
PMID: 33169015
Impaired protein stability or trafficking underlies diverse ion channelopathies and represents an unexploited unifying principle for developing common treatments for otherwise dissimilar diseases. Ubiquitination limits ion channel surface density, but...
6.
Puckerin A, Chang D, Shuja Z, Choudhury P, Scholz J, Colecraft H
Proc Natl Acad Sci U S A
. 2018 Nov;
115(47):12051-12056.
PMID: 30397133
Genetically encoded inhibitors for voltage-dependent Ca (Ca) channels (GECCIs) are useful research tools and potential therapeutics. Rad/Rem/Rem2/Gem (RGK) proteins are Ras-like G proteins that potently inhibit high voltage-activated (HVA) Ca...
7.
Bardoni R, Tawfik V, Wang D, Francois A, Solorzano C, Shuster S, et al.
Neuron
. 2017 Sep;
81(6):1443.
PMID: 28898633
No abstract available.
8.
Takazawa T, Choudhury P, Tong C, Conway C, Scherrer G, Flood P, et al.
J Neurosci
. 2017 Jan;
37(9):2336-2348.
PMID: 28130358
The superficial dorsal horn is the synaptic termination site for many peripheral sensory fibers of the somatosensory system. A wide range of sensory modalities are represented by these fibers, including...
9.
Bardoni R, Tawfik V, Wang D, Francois A, Solorzano C, Shuster S, et al.
Neuron
. 2014 Mar;
81(6):1312-1327.
PMID: 24583022
Cutaneous mechanosensory neurons detect mechanical stimuli that generate touch and pain sensation. Although opioids are generally associated only with the control of pain, here we report that the opioid system...
10.
Bardoni R, Takazawa T, Tong C, Choudhury P, Scherrer G, MacDermott A
Ann N Y Acad Sci
. 2013 Mar;
1279:90-6.
PMID: 23531006
Sensory information transmitted to the spinal cord dorsal horn is modulated by a complex network of excitatory and inhibitory interneurons. The two main inhibitory transmitters, GABA and glycine, control the...